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Ingrid H. Sarelius, Ph.D.

Ingrid H. Sarelius, Ph.D.

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About Me

Faculty Appointments

Professor Emeritus - Department of Pharmacology and Physiology (SMD)

Credentials

Education

PhD | University of Auckland, New Zealand. Physiology. 1978

MSc(Hons) | Massey University. Physiology. 1972

BSc | Massey University. Physiology. 1968

Research

My research focus is on vascular cell communication and signaling. Our lab is specifically interested in how the cells of the blood vessel wall communicate with each other, with the surrounding tissue, and with the blood itself. Basically, we're interested in figuring out how microvessels work! Sinc...
My research focus is on vascular cell communication and signaling. Our lab is specifically interested in how the cells of the blood vessel wall communicate with each other, with the surrounding tissue, and with the blood itself. Basically, we're interested in figuring out how microvessels work! Since cardiovascular disease is a major killer of adult populations, and since much of this is vascular disease or disorder, understanding normal blood vessel function seems like a good place to start.
The major tool that we use to ask our questions is confocal immunofluorescent intravital microscopy; we are one of a handful of labs worldwide that is able to image local events in cells of the vascular wall in real time in blood perfused microvessels in living animals. We also use single microparticle tracking to define the local fluid dynamic environment in vivo, and confocal imaging of signaling molecules and leukocyte populations in the in situ blood vessel.

Publications

Journal Articles

Sarelius IH, Titus PA, Maimon N, Okech W, Wilke-Mounts SJ, Brennan JR, Hocking DC

The Journal of physiology.. 2016 February 1594 (3):687-97. Epub 01/15/2016.

Murrant CL, Sarelius IH

The Journal of physiology.. 2015 November 1593 (21):4699-711. Epub 09/29/2015.

Sarelius IH, Glading AJ

Tissue barriers.. 2015 3 (1-2):e985954. Epub 04/03/2015.

Rocheleau AD, Sumagin R, Sarelius IH, King MR

PloS one.. 2015 10 (6):e0128378. Epub 06/19/2015.

Distefano PV, Kuebel JM, Sarelius IH, Glading AJ

The Journal of biological chemistry.. 2014 November 21289 (47):33054-65. Epub 10/15/2014.

Maimon N, Titus PA, Sarelius IH

The Journal of physiology.. 2014 June 15592 (12):2575-90. Epub 03/31/2014.

Sumagin R, Sarelius IH

Microcirculation : the official journal of the Microcirculatory Society, Inc.. 2013 November 20 (8):679-92. Epub 1900 01 01.

Corr M, Lerman I, Keubel JM, Ronacher L, Misra R, Lund F, Sarelius IH, Glading AJ

Arteriosclerosis, thrombosis, and vascular biology.. 2012 November 32 (11):2702-10. Epub 08/23/2012.

Hyun YM, Sumagin R, Sarangi PP, Lomakina E, Overstreet MG, Baker CM, Fowell DJ, Waugh RE, Sarelius IH, Kim M

The Journal of experimental medicine.. 2012 July 2209 (7):1349-62. Epub 06/18/2012.

Sumagin R, Kuebel JM, Sarelius IH

American journal of physiology. Cell physiology.. 2011 October 301 (4):C804-13. Epub 06/08/2011.

Sumagin R, Prizant H, Lomakina E, Waugh RE, Sarelius IH

The Journal of immunology : official journal of the American Association of Immunologists.. 2010 December 1185 (11):7057-66. Epub 10/29/2010.

Sarelius I, Pohl U

Acta physiologica. 2010 August 199 (4):349-65. Epub 03/26/2010.

Sumagin R, Sarelius IH

The Journal of immunology : official journal of the American Association of Immunologists.. 2010 May 1184 (9):5242-52. Epub 04/02/2010.

Sumagin R, Lamkin-Kennard KA, Sarelius IH

Microcirculation : the official journal of the Microcirculatory Society, Inc.. 2009 August 16 (6):508-20. Epub 05/26/2009.

Lee J, Jirapatnakul AC, Reeves AP, Crowe WE, Sarelius IH

Annals of biomedical engineering.. 2009 May 37 (5):913-26. Epub 03/11/2009.

Sumagin R, Lomakina E, Sarelius IH

American journal of physiology. Heart and circulatory physiology.. 2008 September 295 (3):H969-H977. Epub 07/18/2008.

Sumagin R, Brown CW, Sarelius IH, King MR

Annals of biomedical engineering.. 2008 April 36 (4):580-5. Epub 03/04/2008.

Hocking DC, Titus PA, Sumagin R, Sarelius IH

Circulation research.. 2008 February 15102 (3):372-9. Epub 11/21/2007.

Sumagin R, Sarelius IH

American journal of physiology. Heart and circulatory physiology.. 2007 November 293 (5):H2786-98. Epub 08/17/2007.

Huxley VH, Wang JJ, Sarelius IH

American journal of physiology. Heart and circulatory physiology.. 2007 August 293 (2):H1196-205. Epub 04/13/2007.

Sarelius IH, Kuebel JM, Wang J, Huxley VH

American journal of physiology. Heart and circulatory physiology.. 2006 January 290 (1):H474-80. Epub 08/26/2005.

Sumagin, R.; Sarelius, I.H.;.

Am J Physiol Heart Circ Physiol. 2006; .

Wojciechowski JC, Sarelius IH

Microcirculation : the official journal of the Microcirculatory Society, Inc.. 2005 June 12 (4):349-59. Epub 1900 01 01.

Solute permeability of in situ skeletal muscle microvessels (Abstract)

Sarelius, I.H.; Kuebel, J.M.; Huxley, V.H.;.

Faseb Journal. 2005; 19: A179.

Lamkin-Kennard KA, Chuang JY, Kim MB, Sarelius IH, King MR

Biorheology. 2005 42 (5):363-83. Epub 1900 01 01.

Kim MB, Sarelius IH

American journal of physiology. Heart and circulatory physiology.. 2004 December 287 (6):H2705-11. Epub 08/26/2004.

Duza T, Sarelius IH

American journal of physiology. Heart and circulatory physiology.. 2004 June 286 (6):H2322-31. Epub 02/12/2004.

King MR, Bansal D, Kim MB, Sarelius IH

Annals of biomedical engineering.. 2004 June 32 (6):803-14. Epub 1900 01 01.

Duza T, Sarelius IH

The Journal of physiology.. 2004 March 1555 (Pt 2):459-69. Epub 12/23/2003.

Murrant CL, Duza T, Kim MB, Cohen KD, Sarelius IH

Acta physiologica Scandinavica. 2004 March 180 (3):231-8. Epub 1900 01 01.

Kim MB, Sarelius IH

Microcirculation : the official journal of the Microcirculatory Society, Inc.. 2004 11 (1):55-67. Epub 1900 01 01.

King MR, Kim MB, Sarelius IH, Hammer DA

Microcirculation : the official journal of the Microcirculatory Society, Inc.. 2003 October 10 (5):401-9. Epub 1900 01 01.

Duza T, Sarelius IH

American journal of physiology. Heart and circulatory physiology.. 2003 July 285 (1):H26-37. Epub 03/13/2003.

Kim MB, Sarelius IH

Microcirculation : the official journal of the Microcirculatory Society, Inc.. 2003 April 10 (2):167-78. Epub 1900 01 01.

Murrant CL, Sarelius IH

American journal of physiology. Regulatory, integrative and comparative physiology.. 2002 April 282 (4):R969-78. Epub 1900 01 01.

Cohen KD, Sarelius IH

The Journal of physiology.. 2002 March 1539 (Pt 2):547-55. Epub 1900 01 01.

Frame MD, Sarelius IH

Microcirculation : the official journal of the Microcirculatory Society, Inc.. 2000 December 7 (6 Pt 1):419-27. Epub 1900 01 01.

Murrant CL, Sarelius IH

American journal of physiology. Heart and circulatory physiology.. 2000 November 279 (5):H2285-94. Epub 1900 01 01.

Murdock RC, Reynolds C, Sarelius IH, Waugh RE

American journal of physiology. Cell physiology.. 2000 October 279 (4):C970-80. Epub 1900 01 01.

Sarelius IH, Cohen KD, Murrant CL

Clinical and experimental pharmacology & physiology.. 2000 October 27 (10):826-9. Epub 1900 01 01.

Cohen KD, Berg BR, Sarelius IH

American journal of physiology. Heart and circulatory physiology.. 2000 June 278 (6):H1916-23. Epub 1900 01 01.

Murrant CL, Sarelius IH

Acta physiologica Scandinavica. 2000 April 168 (4):531-41. Epub 1900 01 01.

Lau KS, Grange RW, Isotani E, Sarelius IH, Kamm KE, Huang PL, Stull JT

Physiological genomics.. 2000 January 242 (1):21-7. Epub 01/24/2000.

Lau KS, Grange RW, Chang WJ, Kamm KE, Sarelius I, Stull JT

FEBS letters.. 1998 July 10431 (1):71-4. Epub 1900 01 01.

Frame MD, Chapman GB, Makino Y, Sarelius IH

Biorheology. 1998 35 (4-5):245-61. Epub 1900 01 01.

Berg BR, Cohen KD, Sarelius IH

The American journal of physiology.. 1997 June 272 (6 Pt 2):H2693-700. Epub 1900 01 01.

Waugh RE, Sarelius IH

The American journal of physiology.. 1996 December 271 (6 Pt 1):C1847-52. Epub 1900 01 01.

Berg BR, Sarelius IH

The American journal of physiology.. 1996 December 271 (6 Pt 2):H2263-73. Epub 1900 01 01.

Frame MD, Sarelius IH

Journal of applied physiology.. 1996 November 81 (5):2105-14. Epub 1900 01 01.

Frame MD, Sarelius IH

Microcirculation : the official journal of the Microcirculatory Society, Inc.. 1996 June 3 (2):233-5. Epub 1900 01 01.

Waugh RE, Hwang WC, Sarelius IH

Pflu?gers Archiv : European journal of physiology.. 1996 431 (6 Suppl 2):R271-2. Epub 1900 01 01.

Frame MD, Sarelius IH

Microcirculation : the official journal of the Microcirculatory Society, Inc.. 1995 December 2 (4):377-85. Epub 1900 01 01.

Frame MD, Sarelius IH

Microvascular research.. 1995 November 50 (3):301-10. Epub 1900 01 01.

Frame MD, Sarelius IH

Circulation research.. 1995 October 77 (4):695-701. Epub 1900 01 01.

Sarelius IH

Journal of applied physiology.. 1995 March 78 (3):763-4. Epub 1900 01 01.

Berg BR, Sarelius IH

The American journal of physiology.. 1995 March 268 (3 Pt 2):H1215-22. Epub 1900 01 01.

Kiani MF, Pries AR, Hsu LL, Sarelius IH, Cokelet GR

The American journal of physiology.. 1994 May 266 (5 Pt 2):H1822-8. Epub 1900 01 01.

Sarelius IH

The American journal of physiology.. 1993 November 265 (5 Pt 2):H1682-7. Epub 1900 01 01.

Frame MD, Sarelius IH

Microvascular research.. 1993 September 46 (2):190-205. Epub 1900 01 01.

Frame MD, Sarelius IH

Circulation research.. 1993 July 73 (1):155-63. Epub 1900 01 01.

Kiani MF, Cokelet GR, Sarelius IH

Microvascular research.. 1993 May 45 (3):219-32. Epub 1900 01 01.

Cokelet GR, Sarelius IH

The American journal of physiology.. 1992 April 262 (4 Pt 2):H1156-63. Epub 1900 01 01.

Sweeney TE, Sarelius IH

The American journal of physiology.. 1990 July 259 (1 Pt 2):H124-36. Epub 1900 01 01.

Sarelius IH

Microvascular research.. 1990 July 40 (1):88-98. Epub 1900 01 01.

Sarelius IH, Huxley VH

The American journal of physiology.. 1990 May 258 (5 Pt 2):R1224-9. Epub 1900 01 01.

Sarelius IH

Respiration physiology.. 1989 October 78 (1):7-17. Epub 1900 01 01.

Sweeney TE, Sarelius IH

Circulation research.. 1989 January 64 (1):112-20. Epub 1900 01 01.

Sarelius IH, Nealey TA, Sweeney TE

Advances in experimental medicine and biology.. 1988 242 :17-21. Epub 1900 01 01.

Sarelius IH

The American journal of physiology.. 1986 June 250 (6 Pt 2):H899-907. Epub 1900 01 01.

Sweeney TE, Sarelius IH

Microvascular research.. 1986 March 31 (2):184-96. Epub 1900 01 01.

Sarelius IH, McKinlay SM

The American journal of physiology.. 1985 April 248 (4 Pt 2):H577-86. Epub 1900 01 01.

Federspiel WJ, Sarelius IH

Microvascular research.. 1984 May 27 (3):273-85. Epub 1900 01 01.

Sarelius IH, Maxwell LC, Gray SD, Duling BR

The American journal of physiology.. 1983 August 245 (2):H368-74. Epub 1900 01 01.

Sarelius IH, Duling BR

The American journal of physiology.. 1982 December 243 (6):H1018-26. Epub 1900 01 01.

Duling BR, Sarelius IH, Jackson WF

International journal of microcirculation, clinical and experimental

Hughes EW, Martin-Body RL, Sarelius IH, Sinclair JD

Clinical and experimental pharmacology & physiology.. 1982 9 (2):119-27. Epub 1900 01 01.

Sarelius IH, Damon DN, Duling BR

The American journal of physiology.. 1981 September 241 (3):H317-24. Epub 1900 01 01.

Sarelius IH, Sinclair JD

The American journal of physiology.. 1981 February 240 (2):H177-84. Epub 1900 01 01.

Malcolm JL, Sarelius IH, Sinclair JD

The Journal of physiology.. 1980 October 307 :503-15. Epub 1900 01 01.

Sinclair JD, Sarelius IH

The New Zealand medical journal.. 1979 November 1490 (647):383-7. Epub 1900 01 01.

Sarelius IH

The Journal of physiology.. 1979 July 292 :391-405. Epub 1900 01 01.

Sarelius IH

The New Zealand medical journal.. 1976 October 1384 (573):275-6. Epub 1900 01 01.

Sarelius IH, Quinn JP

The New Zealand medical journal.. 1975 June 2581 (542):549-52. Epub 1900 01 01.

Sarelius IH, Greenway RM

Pflu?gers Archiv : European journal of physiology.. 1975 March 26355 (3):243-59. Epub 1900 01 01.

Books

Microvascular Research: Biology and Pathology (2005)

Chapter: Vascular control mechanisms in skeletal muscle.

Authors: Sarelius, I.H.

Publisher: Academic Press 2005