Jeffrey Michael Purkerson, Ph.D.
Contact
Jeffrey Michael Purkerson, Ph.D.
About Me
Faculty Appointments
Research Associate Professor - Department of Pediatrics, Neonatology (SMD)
Credentials
Post-doctoral Training & Residency
Molecular Genetics and Microbiology Postdoctoral Fellowship, University of Massachusetts Medical Center, Worcester, MA 1994 - 1995
Immunoinflammatory Diseases Research Postdoctoral Fellowship, Searle Research and Development, Monsanto Company. 1991 - 1993
Education
PhD | University of Virginia. Pharmacology. 1991
BS | California Polytechnic State University. Biochemistry. 1986
Research
1) Cell biology and physiology of the carbonic anhydrases
2) The response of renal epithelial cells to acid-base disturbances or injury.
1) Cell biology and physiology of the carbonic anhydrases
2) The response of renal epithelial cells to acid-base disturbances or injury.
Publications
Journal Articles
Saxena V, Hains DS, Ketz J, Chanley M, Spencer JD, Becknell B, Pierce KR, Nelson RD, Purkerson JM, Schwartz GJ, Schwaderer AL
American journal of physiology. Renal physiology.. 2018 October 1315 (4):F812-F823. Epub 05/03/2017.
Peng H, Purkerson JM, Schwaderer AL, Schwartz GJ
American journal of physiology. Renal physiology.. 2017 November 1313 (5):F1061-F1067. Epub 07/26/2017.
Schwartz GJ, Gao X, Tsuruoka S, Purkerson JM, Peng H, D'Agati V, Picard N, Eladari D, Al-Awqati Q
The Journal of clinical investigation.. 2015 October 26125 (12):4365-74. Epub 10/26/2015.
Purkerson JM, Schwaderer AL, Nakamori A, Schwartz GJ
American journal of physiology. Renal physiology.. 2015 September 1309 (5):F464-73. Epub 06/17/2015.
Renal Intercalated cells are rather energized by a proton than a sodium-pump.
Chambrey, R.; Kurth. I.;Peti-Peterdi J.;Houillier, P.;Purkerson, J.;Leviel,F.;Zbedik, A.;Schwartz,G.J.;Huebner,C.;Eladari, D.
PNAS. 2013; .
Adaptation to metabolic acidosis and its recovery are associated with changes in anion exchanger distribution and expression in the cortical collecting duct
Purkerson JM; Tsuruoka S; Suter DZ; Nakamori A; Schwartz GJ.
Kindney International. 2010; 78(10): 993-1005.
Secreted cyclophilin A, a peptidylprolyl cis-trans isomerase, mediates matrix assembly of hensin, a protein implicated in epithelial differentiation.
Peng H, Vijayakumar S, Schiene-Fischer C, Li H, Purkerson JM, Malesevic M, Liebscher J, Al-Awqati, Schwartz GJ.
Journal of Biological Chemistry. 2009; 284(10): 6465-75.
Secreted cyclophilin A, a peptidylprolyl cis-trans isomerase, mediates matrix assembly of hensin, a protein implicated in epithelial differentiation.
Peng H; Vijayakumar S; Schiene-Fischer C; Li H; Purkerson JM; Malesevic M; Liebscher J; Al-Awqati Q; Schwartz GJ.
Journal of Biological Chemistry. 2008; 284(10): 6465-75.
Purkerson JM, Kittelberger AM, Schwartz GJ
Kidney international.. 2007 March 71 (5):407-16. Epub 01/17/2007.
Tsuruoka S, Watanabe S, Purkerson JM, Fujimura A, Schwartz GJ
American journal of physiology. Renal physiology.. 2006 October 291 (4):F866-73. Epub 05/16/2006.
Purkerson JM, Smith RS, Pollock SJ, Phipps RP
European journal of immunology.. 2005 October 35 (10):2920-8. Epub 1900 01 01.
Purkerson JM, Schwartz GJ
American journal of physiology. Regulatory, integrative and comparative physiology.. 2005 May 288 (5):R1256-63. Epub 1900 01 01.
Tsuruoka S, Schwartz GJ, Wakaumi M, Nishiki K, Yamamoto H, Purkerson JM, Fujimura A
The Journal of pharmacology and experimental therapeutics.. 2003 June 305 (3):840-5. Epub 03/06/2003.
Hwang Y, Nahm MH, Briles DE, Thomas D, Purkerson JM
Infection and immunity.. 2000 February 68 (2):511-7. Epub 1900 01 01.
Evans DE, Munks MW, Purkerson JM, Parker DC
The Journal of immunology : official journal of the American Association of Immunologists.. 2000 January 15164 (2):688-97. Epub 1900 01 01.
Purkerson JM, Parker DC
The Journal of immunology : official journal of the American Association of Immunologists.. 1998 March 1160 (5):2121-9. Epub 1900 01 01.
IL-5 receptor expression and Ig secretion from murine B lymphocytes requires coordinated signaling by membrane Ig , IL-4, and IL-5.
Weber JD; Isakson PC; Purkerson JM.
Journal of Immunology. 1996; 157(10): 4428-35.
Purkerson JM, Isakson PC
The Journal of experimental medicine.. 1994 June 1179 (6):1877-83. Epub 1900 01 01.
Purkerson J, Isakson P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.. 1992 November 6 (14):3245-52. Epub 1900 01 01.
Purkerson JM, Isakson PC
The Journal of experimental medicine.. 1992 April 1175 (4):973-82. Epub 1900 01 01.
Constitutive versus cell cycle regulation of c-myb mRNA expression correlates with developmental stages in murine B lymphoid tumors.
Catron KM; Purkerson JM; Isakson PC; Bender TP.
Journal of Immunology. 1992; 148(3): 934-42.
Isakson PC, Purkerson J, Catron K, Bender TP
Journal of immunological methods.. 1991 December 15145 (1-2):137-42. Epub 1900 01 01.
Purkerson JM, Isakson PC
European journal of immunology.. 1991 March 21 (3):707-14. Epub 1900 01 01.
Catron KM, Toth CR, Purkerson J, Isakson P, Bender TP
Current topics in microbiology and immunology.. 1990 166 :197-202. Epub 1900 01 01.
Purkerson JM, Newberg M, Wise G, Lynch KR, Isakson PC
The Journal of experimental medicine.. 1988 September 1168 (3):1175-80. Epub 1900 01 01.
Books
Trends in Atherosclerosis Research (2004)
Chapter: Targeting of the CD40-CD40 (CD154) Ligand System as Therapeutic Intervention for the Treatment of Atherosclerosis
Authors: Carolyn J. Baglole, Richard P. Phipps, Jeffrey M. Purkerson, Patricia J. Sime
Publisher: Nova Science Publishers Inc., New York, NY 2004
Cytokine regulation of humoral immunity: Basic and clinical aspects (1996)
Chapter: B-cell activation and maturation to immunoglobulin secretion
Authors: Parker DC, Purkerson JM
Publisher: John Wiley & Sons, New York, NY 1996