麻豆视频

Skip to content
Home
David A. Dean, Ph.D.

David A. Dean, Ph.D.

Contact

Looking for more Information?

Visit my lab website to learn more about my research, collaborators, latest news, etc.

About Me

Faculty Appointments

Professor - Department of Pediatrics, Neonatology (SMD)

Credentials

Post-doctoral Training & Residency

University of California, Los Angeles Postdoctoral Fellow Virology 1990 - 1994

Education

PhD | University of California at Berkeley. Microbiology. 1990

PhD | University of California, Berkeley. Microbiology. 1990

BA | University of California at San Diego. Biochemistry. 1985

Awards

Keynote Speaker. 2019

Chair. 2014

Keynote Speaker. 2013

Co-Chair. 2012

Ruth A. Lawrence Academic Faculty Service Award in Research. 2011

Mentoring the Mentors. 2006

Sandler Program for Asthma Research Senior Investigator. 2005

NIH Individual Postdoctoral Fellowship (NRSA). 1991 - 1994

President's Undergraduate Scholarship. 1984

Research

Despite all of the hype regarding gene therapy, at present, gene therapy is a dream due to insufficient levels of gene transfer and expression at desired sites. One way to increase gene expression is to target more DNA to the cell nucleus. Since the nucleus is the site of transcription, without th...
Despite all of the hype regarding gene therapy, at present, gene therapy is a dream due to insufficient levels of gene transfer and expression at desired sites. One way to increase gene expression is to target more DNA to the cell nucleus. Since the nucleus is the site of transcription, without the movement of plasmids through the cytoplasm, translocation into the nucleus, and localization to the appropriate subnuclear domain, no gene expression, or "gene therapy" can take place. Ongoing projects in my laboratory are studying the mechanisms of cytoplasmic trafficking of plasmids along the cytoskeleton, plasmid nuclear entry, subnuclear organization, and exploiting what we learn to improve gene therapy.


We have shown that plasmids are able to enter the nucleus in a sequence-specific manner that appears to be mediated by transcription factor binding. My lab is interested in identifying the proteins required for this activity and the regulation of their nuclear import. Based on our model, we have created cell-specific plasmids by incorporating DNA sequences that bind to cell-specific transcription factors. At present, we have examples of smooth muscle, alveolar epithelial cell, and endothelial cell-targeting vectors that we hope to use for the treatment of a number of pulmonary diseases, and we are working to expand our repertoire to selectively target expression to any desired cell or tissue.


We also are developing methods for extracellular delivery of non-viral vectors in animal models for disease. Using electroporation, we have obtained very high levels of gene expression in the vasculature and lungs of animals. We have used this approach to prevent and/or cure existing disease in models of acute lung injury and asthma in mice and rats. Our next goal is to optimize these approaches in more relevant preclinical models to move toward clinical application.

Publications

Journal Articles

Millar MW, Najar RA, Slavin SA, Shadab M, Tahir I, Mahamed Z, Lin X, Abe JI, Wright TW, Dean DA, Fazal F, Rahman A

The Journal of biological chemistry.. 2024 November 5 :107952. Epub 11/05/2024.

Lin X, Bai H, Barravecchia M, Norman R, Schiralli Lester GM, Kottmann RM, Leonard A, Rahman A, Young JL, Dean DA

International journal of molecular sciences.. 2024 October 2925 (21)Epub 10/29/2024.

Jagrosse ML, Baliga UK, Jones CW, Russell JJ, Garc铆a CI, Najar RA, Rahman A, Dean DA, Nilsson BL

Molecular pharmaceutics.. 2023 December 420 (12):6090-6103. Epub 11/14/2023.

Shadab M, Slavin SA, Mahamed Z, Millar MW, Najar RA, Leonard A, Pietropaoli A, Dean DA, Fazal F, Rahman A

The Journal of biological chemistry.. 2023 December 299 (12):105408. Epub 10/28/2023.

Gurunian A, Dean DA

Bioelectrochemistry.. 2023 June 151 :108396. Epub 02/11/2023.

Liu J, Schiralli-Lester GM, Norman R, Dean DA

Scientific reports.. 2023 April 2613 (1):6792. Epub 04/26/2023.

Gurunian A, Dean DA

Bioelectrochemistry.. 2022 October 147 :108162. Epub 05/19/2022.

Liu J, Dean DA

Scientific reports.. 2021 October 2111 (1):20862. Epub 10/21/2021.

Bai H, Zhou R, Barravecchia M, Norman R, Friedman AE, Yu D, Lin X, Young JL, Dean DA

JCI insight.. 2021 February 226 (4)Epub 02/22/2021.

Baliga UK, Dean DA

Experimental biology and medicine. 2021 February 246 (3):260-274. Epub 11/12/2020.

Eliseeva SI, Knowlden ZA, Lester GM, Dean DA, Georas SN, Chapman TJ

Scientific reports.. 2021 January 1411 (1):1453. Epub 01/14/2021.

Welch JJ, Dean DA, Nilsson BL

Methods in molecular biology.. 2021 2208 :49-67. Epub 1900 01 01.

Liu J, Dean DA

Frontiers in physiology.. 2021 12 :786255. Epub 01/17/2022.

Steiner LA, Getman M, Schiralli Lester GM, Iqbal MA, Katzman P, Szafranski P, Stankiewicz P, Bhattacharya S, Mariani T, Pryhuber G, Lin X, Young JL, Dean DA, Scheible K

Journal of medical genetics.. 2020 May 57 (5):296-300. Epub 10/29/2019.

脕vila-P茅rez G, Nogales A, Park JG, Vasquez DM, Dean DA, Barravecchia M, Perez DR, Almaz谩n F, Mart铆nez-Sobrido L

Scientific reports.. 2020 January 1610 (1):512. Epub 01/16/2020.

Jagrosse ML, Dean DA, Rahman A, Nilsson BL

Translational research : the journal of laboratory and clinical medicine.. 2019 December 214 :30-49. Epub 07/27/2019.

Leonard A, Millar MW, Slavin SA, Bijli KM, Dionisio Santos, Dean DA, Fazal F, Rahman A

Cellular signalling.. 2019 September 61 :120-129. Epub 05/01/2019.

Bai H, Schiralli Lester GM, Petishnok LC, Dean DA

Bioscience reports.. 2017 December 2237 (6)Epub 11/29/2017.

Barnett RC, Lin X, Barravecchia M, Norman RA, de Mesy Bentley KL, Fazal F, Young JL, Dean DA

Experimental biology and medicine. 2017 July 242 (13):1345-1354. Epub 06/05/2017.

Rahmani K, Dean DA

Biochemical and biophysical research communications.. 2017 June 24488 (2):253-258. Epub 04/12/2017.

Parikh P, Bai H, Swartz MF, Alfieris GM, Dean DA

Experimental biology and medicine. 2016 December 241 (18):2112-2118. Epub 07/28/2016.

Gottfried L, Lin X, Barravecchia M, Dean DA

Gene therapy.. 2016 October 23 (10):734-742. Epub 07/01/2016.

Welch JJ, Swanekamp RJ, King C, Dean DA, Nilsson BL

ACS medicinal chemistry letters.. 2016 June 97 (6):584-9. Epub 03/30/2016.

Lin X, Barravecchia M, Kothari P, Young JL, Dean DA

Gene therapy.. 2016 June 23 (6):489-99. Epub 03/17/2016.

Vernon MM, Dean DA, Dobson J

International journal of molecular sciences.. 2015 August 1716 (8):19369-86. Epub 08/17/2015.

Huber AR, Tan D, Sun J, Dean D, Wu T, Zhou Z

BMC gastroenterology.. 2015 July 915 :80. Epub 07/09/2015.

Emr BM, Roy S, Kollisch-Singule M, Gatto LA, Barravecchia M, Lin X, Young JL, Wang G, Liu J, Satalin J, Snyder K, Nieman GF, Dean DA

Shock.. 2015 January 43 (1):16-23. Epub 1900 01 01.

Young JL, Dean DA

Advances in genetics.. 2015 89 :49-88. Epub 12/11/2014.

Young JL, Barravecchia MS, Dean DA

Methods in molecular biology.. 2014 1121 :189-204. Epub 1900 01 01.

Emr B, Gatto LA, Roy S, Satalin J, Ghosh A, Snyder K, Andrews P, Habashi N, Marx W, Ge L, Wang G, Dean DA, Vodovotz Y, Nieman G

JAMA surgery.. 2013 November 148 (11):1005-12. Epub 1900 01 01.

Dean DA

The Journal of membrane biology.. 2013 October 246 (10):737-44. Epub 03/24/2013.

Roy SK, Emr B, Sadowitz B, Gatto LA, Ghosh A, Satalin JM, Snyder KP, Ge L, Wang G, Marx W, Dean D, Andrews P, Singh A, Scalea T, Habashi N, Nieman GF

Shock.. 2013 September 40 (3):210-6. Epub 1900 01 01.

Badding MA, Dean DA

Gene therapy.. 2013 June 20 (6):616-24. Epub 09/27/2012.

Badding MA, Lapek JD, Friedman AE, Dean DA

Molecular therapy : the journal of the American Society of Gene Therapy.. 2013 April 21 (4):775-85. Epub 11/20/2012.

Roy S, Habashi N, Sadowitz B, Andrews P, Ge L, Wang G, Roy P, Ghosh A, Kuhn M, Satalin J, Gatto LA, Lin X, Dean DA, Vodovotz Y, Nieman G

Shock.. 2013 January 39 (1):28-38. Epub 1900 01 01.

Cramer F, Christensen CL, Poulsen TT, Badding MA, Dean DA, Poulsen HS

Cancer gene therapy.. 2012 October 19 (10):675-83. Epub 08/17/2012.

O'Reilly MA, Yee M, Buczynski BW, Vitiello PF, Keng PC, Welle SL, Finkelstein N, Dean DA, Lawrence BP

The American journal of pathology.. 2012 August 181 (2):441-51. Epub 06/05/2012.

Roy S, Sadowitz B, Andrews P, Gatto LA, Marx W, Ge L, Wang G, Lin X, Dean DA, Kuhn M, Ghosh A, Satalin J, Snyder K, Vodovotz Y, Nieman G, Habashi N

The journal of trauma and acute care surgery.. 2012 August 73 (2):391-400. Epub 1900 01 01.

Yao H, Chung S, Hwang JW, Rajendrasozhan S, Sundar IK, Dean DA, McBurney MW, Guarente L, Gu W, R枚nty M, Kinnula VL, Rahman I

The Journal of clinical investigation.. 2012 June 122 (6):2032-45. Epub 05/01/2012.

Badding MA, Vaughan EE, Dean DA

Gene therapy.. 2012 March 19 (3):338-46. Epub 06/30/2011.

Badding MA, Vaughan EE, Dean DA

Gene therapy.. 2012 March 19 (3):354. Epub 07/21/2011.

Lin X, Dean DA

Critical care clinics.. 2011 July 27 (3):705-18. Epub 1900 01 01.

Eldib M, Dean DA

Biotechnology and bioengineering.. 2011 February 108 (2):446-53. Epub 1900 01 01.

Use of Electroporation for Efficacious Gene Delivery to the Lungs

Dean, D. A., M. Barravecchia, B. Danziger, and X. Lin.

ECS Trans. 2011; 35: 167-177.

Staversky RJ, Vitiello PF, Yee M, Callahan LM, Dean DA, O'Reilly MA

American journal of respiratory cell and molecular biology.. 2010 September 43 (3):376-85. Epub 10/30/2009.

Kaufman CD, Geiger RC, Dean DA

Gene therapy.. 2010 September 17 (9):1098-104. Epub 04/29/2010.

Degiulio JV, Kaufman CD, Dean DA

Gene therapy.. 2010 April 17 (4):541-9. Epub 01/07/2010.

Lam AP, Dean DA

Gene therapy.. 2010 April 17 (4):439-47. Epub 03/04/2010.

Wang Y, Heilig KO, Minto AW, Chen S, Xiang M, Dean DA, Geiger RC, Chang A, Pravtcheva DD, Schlimme M, Deb DK, Wang Y, Heilig CW

Laboratory investigation; a journal of technical methods and pathology.. 2010 January 90 (1):83-97. Epub 11/16/2009.

Miller AM, Munkonge FM, Alton EW, Dean DA

Molecular therapy : the journal of the American Society of Gene Therapy.. 2009 November 17 (11):1897-903. Epub 06/16/2009.

Yee M, Chess PR, McGrath-Morrow SA, Wang Z, Gelein R, Zhou R, Dean DA, Notter RH, O'Reilly MA

American journal of physiology. Lung cellular and molecular physiology.. 2009 October 297 (4):L641-9. Epub 07/17/2009.

Munkonge FM, Amin V, Hyde SC, Green AM, Pringle IA, Gill DR, Smith JW, Hooley RP, Xenariou S, Ward MA, Leeds N, Leung KY, Chan M, Hillery E, Geddes DM, Griesenbach U, Postel EH, Dean DA, Dunn MJ, Alton EW

The Journal of biological chemistry.. 2009 September 25284 (39):26978-87. Epub 07/28/2009.

Aistrup GL, Villuendas R, Ng J, Gilchrist A, Lynch TW, Gordon D, Cokic I, Mottl S, Zhou R, Dean DA, Wasserstrom JA, Goldberger JJ, Kadish AH, Arora R

Cardiovascular research.. 2009 August 183 (3):481-92. Epub 05/20/2009.

Miller AM, Dean DA

Advanced drug delivery reviews.. 2009 July 261 (7-8):603-13. Epub 04/23/2009.

Xavier J, Singh S, Dean DA, Rao NM, Gopal V

Journal of controlled release : official journal of the Controlled Release Society.. 2009 January 19133 (2):154-60. Epub 10/11/2008.

Geiger RC, Kaufman CD, Lam AP, Budinger GR, Dean DA

American journal of respiratory cell and molecular biology.. 2009 January 40 (1):76-82. Epub 07/17/2008.

Vaughan EE, Geiger RC, Miller AM, Loh-Marley PL, Suzuki T, Miyata N, Dean DA

Molecular therapy : the journal of the American Society of Gene Therapy.. 2008 November 16 (11):1841-7. Epub 09/09/2008.

Miller AM, Dean DA

Gene therapy.. 2008 August 15 (15):1107-15. Epub 05/22/2008.

Young JL, Zimmer WE, Dean DA

Experimental biology and medicine. 2008 July 233 (7):840-8. Epub 04/29/2008.

Lam AP, Dean DA

The journal of gene medicine.. 2008 June 10 (6):668-78. Epub 1900 01 01.

Dean DA, Ramanathan T, Machado D, Sundararajan R

Journal of electrostatics.. 2008 March 66 (3-4):165-177. Epub 1900 01 01.

Quantifying Induced Electric Field Strengths During Gene Transfer to the Intact Rat Vasculature.

Capaccio, C.; Stoykov, N.S.; Sundarajan, R.; and D.A. Dean.

J Electrostatics. 2008; : (in press).

Zhou R, Norton JE, Dean DA

Methods in molecular biology.. 2008 423 :233-47. Epub 1900 01 01.

Gasiorowski JZ, Dean DA

Molecular therapy : the journal of the American Society of Gene Therapy.. 2007 December 15 (12):2132-9. Epub 07/31/2007.

Mutlu GM, Green D, Bellmeyer A, Baker CM, Burgess Z, Rajamannan N, Christman JW, Foiles N, Kamp DW, Ghio AJ, Chandel NS, Dean DA, Sznajder JI, Budinger GR

The Journal of clinical investigation.. 2007 October 117 (10):2952-61. Epub 1900 01 01.

Mutlu GM, Machado-Aranda D, Norton JE, Bellmeyer A, Urich D, Zhou R, Dean DA

American journal of respiratory and critical care medicine.. 2007 September 15176 (6):582-90. Epub 06/07/2007.

Zhou R, Norton JE, Zhang N, Dean DA

Gene therapy.. 2007 May 14 (9):775-80. Epub 03/08/2007.

Bellmeyer A, Martino JM, Chandel NS, Scott Budinger GR, Dean DA, Mutlu GM

American journal of respiratory and critical care medicine.. 2007 March 15175 (6):587-94. Epub 12/21/2006.

Zhou R, Dean DA

Experimental biology and medicine. 2007 March 232 (3):362-9. Epub 1900 01 01.

Kopp K, Gasiorowski JZ, Chen D, Gilmore R, Norton JT, Wang C, Leary DJ, Chan EK, Dean DA, Huang S

Molecular biology of the cell.. 2007 February 18 (2):394-403. Epub 11/15/2006.

Quantifying Induced Electric Field Strengths During Gene Transfer to the Intact Rat Vasculature.

Capaccio, C., N. S. Stoykov, R. Sundararajan, and D. A. Dean.

IEEE Trans. Biomed. Eng. 2007; .

Vaughan EE, DeGiulio JV, Dean DA

Current gene therapy.. 2006 December 6 (6):671-681. Epub 1900 01 01.

Hillery E, Munkonge FM, Xenariou S, Dean DA, Alton EW

Analytical biochemistry.. 2006 May 15352 (2):169-75. Epub 03/09/2006.

Geiger RC, Taylor W, Glucksberg MR, Dean DA

Gene therapy.. 2006 April 13 (8):725-31. Epub 1900 01 01.

Vaughan EE, Dean DA

Molecular therapy : the journal of the American Society of Gene Therapy.. 2006 February 13 (2):422-8. Epub 11/21/2005.

Gasiorowski JZ, Dean DA

Molecular therapy : the journal of the American Society of Gene Therapy.. 2005 September 12 (3):460-7. Epub 1900 01 01.

Dean DA

American journal of physiology. Cell physiology.. 2005 August 289 (2):C233-45. Epub 1900 01 01.

Jones JC, Lane K, Hopkinson SB, Lecuona E, Geiger RC, Dean DA, Correa-Meyer E, Gonzales M, Campbell K, Sznajder JI, Budinger S

Journal of cell science.. 2005 June 15118 (Pt 12):2557-66. Epub 05/31/2005.

Dean DA, Strong DD, Zimmer WE

Gene therapy.. 2005 June 12 (11):881-90. Epub 1900 01 01.

Machado-Aranda D, Adir Y, Young JL, Briva A, Budinger GR, Yeldandi AV, Sznajder JI, Dean DA

American journal of respiratory and critical care medicine.. 2005 February 1171 (3):204-11. Epub 10/29/2004.

Wang L, Dean DA, Macdonald RC

Current drug delivery.. 2005 January 2 (1):93-6. Epub 1900 01 01.

Zhou R, Geiger RC, Dean DA

Expert opinion on drug delivery.. 2004 November 1 (1):127-40. Epub 1900 01 01.

Zhang G, Gao X, Song YK, Vollmer R, Stolz DB, Gasiorowski JZ, Dean DA, Liu D

Gene therapy.. 2004 April 11 (8):675-82. Epub 1900 01 01.

Dean DA

DNA and cell biology.. 2003 December 22 (12):797-806. Epub 1900 01 01.

Nunamaker EA, Zhang HY, Shirasawa Y, Benoit JN, Dean DA

American journal of physiology. Heart and circulatory physiology.. 2003 November 285 (5):H2240-7. Epub 07/24/2003.

Dean DA, Machado-Aranda D, Blair-Parks K, Yeldandi AV, Young JL

Gene therapy.. 2003 September 10 (18):1608-15. Epub 1900 01 01.

Young JL, Benoit JN, Dean DA

Gene therapy.. 2003 August 10 (17):1465-70. Epub 1900 01 01.

Gasiorowski JZ, Dean DA

Advanced drug delivery reviews.. 2003 June 1655 (6):703-16. Epub 1900 01 01.

Munkonge FM, Dean DA, Hillery E, Griesenbach U, Alton EW

Advanced drug delivery reviews.. 2003 June 1655 (6):749-60. Epub 1900 01 01.

Shirasawa Y, Rutland TJ, Young JL, Dean DA, Joseph BN

Frontiers in bioscience : a journal and virtual library.. 2003 May 18 :a133-8. Epub 05/01/2003.

Taylor W, Gokay KE, Capaccio C, Davis E, Glucksberg M, Dean DA

Molecular therapy : the journal of the American Society of Gene Therapy.. 2003 April 7 (4):542-9. Epub 1900 01 01.

Budinger GR, Tso M, McClintock DS, Dean DA, Sznajder JI, Chandel NS

The Journal of biological chemistry.. 2002 May 3277 (18):15654-60. Epub 02/27/2002.

Hirschi KK, Lai L, Belaguli NS, Dean DA, Schwartz RJ, Zimmer WE

The Journal of biological chemistry.. 2002 February 22277 (8):6287-95. Epub 12/11/2001.

Young JL, Dean DA

Microcirculation : the official journal of the Microcirculatory Society, Inc.. 2002 January 9 (1):35-49. Epub 1900 01 01.

Blair-Parks K, Weston BC, Dean DA

The journal of gene medicine.. 2002 4 (1):92-100. Epub 1900 01 01.

Filmore RA, Dean DA, Zimmer WE

Gene expression.. 2002 10 (5-6):201-11. Epub 1900 01 01.

Dean DA, Perkin RA

American family physician.. 2001 May 163 (9):1707, 1710, 1715-6. Epub 1900 01 01.

Li S, MacLaughlin FC, Fewell JG, Gondo M, Wang J, Nicol F, Dean DA, Smith LC

Gene therapy.. 2001 March 8 (6):494-7. Epub 1900 01 01.

Dean DA, Urban G, Aragon IV, Swingle M, Miller B, Rusconi S, Bueno M, Dean NM, Honkanen RE

BMC cell biology.. 2001 2 :6. Epub 05/17/2001.

Dean DA

Advanced drug delivery reviews.. 2000 November 1544 (2-3):81-95. Epub 1900 01 01.

Norwood N, Moore TM, Dean DA, Bhattacharjee R, Li M, Stevens T

American journal of physiology. Lung cellular and molecular physiology.. 2000 November 279 (5):L815-24. Epub 1900 01 01.

Bustamante JO, Michelette ER, Geibel JP, Hanover JA, McDonnell TJ, Dean DA

Pflu?gers Archiv : European journal of physiology.. 2000 April 439 (6):829-37. Epub 1900 01 01.

Bustamante JO, Michelette ER, Geibel JP, Dean DA, Hanover JA, McDonnell TJ

Pflu?gers Archiv : European journal of physiology.. 2000 February 439 (4):433-44. Epub 1900 01 01.

Martin JB, Young JL, Benoit JN, Dean DA

Journal of vascular research.. 2000 37 (5):372-80. Epub 1900 01 01.

Dean DA, Dean BS, Muller S, Smith LC

Experimental cell research.. 1999 December 15253 (2):713-22. Epub 1900 01 01.

Reddy JA, Dean D, Kennedy MD, Low PS

Journal of pharmaceutical sciences.. 1999 November 88 (11):1112-8. Epub 1900 01 01.

Wilson GL, Dean BS, Wang G, Dean DA

The Journal of biological chemistry.. 1999 July 30274 (31):22025-32. Epub 1900 01 01.

Wang G, Xu X, Pace B, Dean DA, Glazer PM, Chan P, Goodman SR, Shokolenko I

Nucleic acids research.. 1999 July 127 (13):2806-13. Epub 1900 01 01.

Dean DA, Byrd JN, Dean BS

Current eye research.. 1999 July 19 (1):66-75. Epub 1900 01 01.

Vacik J, Dean BS, Zimmer WE, Dean DA

Gene therapy.. 1999 June 6 (6):1006-14. Epub 1900 01 01.

Tran MT, Dean DA, Lausch RN, Oakes JE

Virology.. 1998 April 25244 (1):74-8. Epub 1900 01 01.

Dean DA

Experimental cell research.. 1997 February 1230 (2):293-302. Epub 1900 01 01.

Dean DA, Li PP, Lee LM, Kasamatsu H

Journal of virology.. 1995 February 69 (2):1115-21. Epub 1900 01 01.

Dean DA, Kasamatsu H

The Journal of biological chemistry.. 1994 February 18269 (7):4910-6. Epub 1900 01 01.

Clever J, Dean DA, Kasamatsu H

The Journal of biological chemistry.. 1993 October 5268 (28):20877-83. Epub 1900 01 01.

Dean DA, Hor LI, Shuman HA, Nikaido H

Molecular microbiology.. 1992 August 6 (15):2033-40. Epub 1900 01 01.

Dean DA, Reizer J, Nikaido H, Saier MH

The Journal of biological chemistry.. 1990 December 5265 (34):21005-10. Epub 1900 01 01.

Dean DA, Davidson AL, Nikaido H

Research in microbiology. 1990 141 (3):348-52. Epub 1900 01 01.

Dean DA, Davidson AL, Nikaido H

Proceedings of the National Academy of Sciences of the United States of America.. 1989 December 86 (23):9134-8. Epub 1900 01 01.

Dean DA, Fikes JD, Gehring K, Bassford PJ, Nikaido H

Journal of bacteriology.. 1989 January 171 (1):503-10. Epub 1900 01 01.

Books

Novel Gene Therapy Approaches (2013)

Chapter: Extracellular and Intracellular Barriers to Non-Viral Gene Transfer

Authors: Gottfried, L., and D. A. Dean

Publisher: Intech Press, Rijecka, Croatia 2013

Electroporation Protocols: Experimental and Clinical Medicine (2013)

Chapter: Electroporation-mediated Gene Delivery to the Lungs

Authors: Young, J. L., M. Barravecchia, and D. A. Dean

Publisher: Humana Press, Totowa, NJ 2013

Optical Imaging Techniques: A Laboratory Manua (2010)

Chapter: Nonviral gene delivery

Authors: Dean, D. A., and J. Z. Gasiorowski

Publisher: Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY 2010

Electroporation in Science and Medicine (2010)

Chapter: Electroporation-mediated gene transfer to the lung

Authors: Dean, DA

Publisher: Springer, New York, NY 2010

Electroporation in Science and Medicine (2010)

Chapter: Electrotransfer of DNA

Authors: Escoffre, J. M., M. P. Rols, and D. A. Dean

Publisher: Springer, New York, NY 2010

Electroporation Protocols: Experimental and Clinical Medicine (in press). (2007)

Chapter: Electroporation-mediated Gene Delivery to the Lungs.

Authors: Zhou, R., J. E. Norton, and D. A. Dean

Publisher: S. Li (Ed). Humana Press, Totowa, NJ 2007

Nucleocytoplasmic Transport (2005)

Chapter: Nuclear import of DNA. .

Authors: Gokay, K. E., and D. A. Dean.

Publisher: T. Tzvi and V. Citovsky (Eds). Landes Bioscience, Georgetown, TX. 2005

Live Cell Imaging: A Laboratory Manual (2004)

Chapter: Improving gene delivery and expression of GFP by cyclic stretch.

Authors: Dean, D. A.

Publisher: D. L. Spector and R. D. Goldman (Eds). Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY 2004

Pharmaceutical perspectives of nucleic acid-based therapeutics (2002)

Chapter: Nucleocytoplasmic trafficking

Authors: Dean, D. A.

Publisher: R. I. Mahato (Ed). Harwood Academic Publishers, London 2002