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Walter Richard Burack, M.D., Ph.D.

Walter Richard Burack, M.D., Ph.D.

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About Me

Dr. Burack is the Vice Chair for Clinical Operations in the Department of Pathology and Laboratory Medicine. Prior to this role, he was director of Hematopathology, which includes the Flow Cytometry Laboratory, tissue banking activities, and the Hematopathology Fellowship Program. This division work...
Dr. Burack is the Vice Chair for Clinical Operations in the Department of Pathology and Laboratory Medicine. Prior to this role, he was director of Hematopathology, which includes the Flow Cytometry Laboratory, tissue banking activities, and the Hematopathology Fellowship Program. This division works closely with Wilmot Cancer Institute and Pediatric Oncology to evaluate and diagnose lymphomas, leukemias, and related disorders.

Certified Specialties

Hematopathology - American Board of Pathology

Pathology, Clinical Pathology/Laboratory Medicine - American Board of Pathology

Faculty Appointments

Professor - Department of Pathology and Laboratory Medicine (SMD)

Professor - Cancer Center - Joint

Credentials

Residency & Fellowship

Fellowship, Hematopathology, Barnes Jewish Hospital. 1998 - 1999

Residency, Pathology - Clinical, University of Virginia Hospitals. 1995 - 1998

Education

MD | University of Virginia School of Medicine. 1995

Awards

2018 Chairman's Recognition Award. 2018

Eric A. Schenk Award for Excellence in Teaching. 2014

Excellence in 2nd Year Teaching. 2010

Class of 2010 Professor of the Year. 2007

Class of 2009 Professor of the Year. 2006

Class of 2008 Lecturer of the Year. 2005

Class of 2006 Distinguished Teacher Award. 2004

Research

Dr. Burack's research interests include the molecular mechanisms of lymphoma progression and development of molecular methods to refine diagnostics, particularly of lymphomas and leukemias. He recently became co-investigator on a grant to study the role of immune-senescence in lymphomagenesis, the r...
Dr. Burack's research interests include the molecular mechanisms of lymphoma progression and development of molecular methods to refine diagnostics, particularly of lymphomas and leukemias. He recently became co-investigator on a grant to study the role of immune-senescence in lymphomagenesis, the role of immune microenvironment in determining response to therapy, and the role of immune function in the symptoms of lymphoma via analysis of rare immune cell populations by advanced flow cytometry.

Research Lab

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Clinical Trials

ULAB-03012~Tissue Procurement Facility Collection of specimens and epidemiological and clinical outcomes data in patients with hematological malignancies 

Lead Researcher: Walter Richard Burack

This research is being done because we hope that a better understanding of hematologic malignancies will allow us to develop new and better treatments.

The Lymphoma Epidemiology of Outcomes (LEO) Cohort Study

Lead Researcher: Walter Richard Burack

The goal of this infrastructure grant is to establish and maintain a cohort of over 12,000 non-Hodgkin lymphoma (NHL) patients to support broad and cutting-edge research that identifies clinical (including co-morbid diseases), epidemiologic (includin...

Publications

Journal Articles

El Hussein S, Fang H, Jelloul FZ, Wang W, Loghavi S, Miranda RN, Friedberg JW, Burack WR, Evans AG, Xu J, Medeiros LJ

Archives of pathology & laboratory medicine.. 2024 August 1148 (8):914-920. Epub 1900 01 01.

Maurer MJ, Casulo C, Larson MC, Habermann TM, Lossos IS, Wang Y, Nastoupil LJ, Strouse C, Chihara D, Martin P, Cohen JB, Kahl BS, Burack WR, Koff JL, Mun Y, Masaquel A, Wu M, Wei MC, Shewade A, Li J, Cerhan JR, Link BK, Flowers CR

Haematologica.. 2024 July 1109 (7):2177-2185. Epub 07/01/2024.

George GV, Aldowitz DG, Jajosky AN, Wallace DS, Burack WR, Friedberg JW, El Hussein S

EJHaem.. 2024 June 5 (3):599-602. Epub 04/24/2024.

George GV, Wallace DS, Wang Y, Carney J, Elsadawi M, Burack WR, Evans AG, Barr PM, Velez MJ, El Hussein S

Histopathology.. 2024 April 84 (5):900-902. Epub 11/30/2023.

Yeo YY, Qiu H, Bai Y, Zhu B, Chang Y, Yeung J, Michel HA, Wright K, Shaban M, Sadigh S, Nkosi D, Shanmugam V, Rock P, Tung Yiu SP, Cramer P, Paczkowska J, Stephan P, Liao G, Huang AY, Wang H, Chen H, Frauenfeld L, Mitra B, Gewurz BE, Schürch CM, Zhao B, Nolan GP, Zhang B, Shalek AK, Angelo M, Mahmood F, Ma Q, Burack WR, Shipp MA, Rodig SJ, Jiang S

bioRxiv : the preprint server for biology.. 2024 March 7 Epub 03/07/2024.

Cerhan JR, Maurer MJ, Link BK, Feldman AL, Habermann TM, Jaye DL, Burack WR, McDonnell TJ, Vega F, Chapman JR, Syrbu S, Vij KR, Inghirami G, Leonard JP, Bernal-Mizrachi L, Farooq U, Witzig TE, Weiner GJ, Wang Y, Alderuccio JP, Slager SL, Larson MC, Riska SM, Gysbers BJ, Lunde JJ, Reicks TW, Ayers AA, O'Leary CB, Yost KJ, Liu H, Nowakowski GS, Ruan J, Chihara D, Koff JL, Casulo C, Thompson CA, Cohen JB, Kahl BS, Nastoupil LJ, Lossos IS, Friedberg JW, Martin P, Flowers CR

American journal of hematology.. 2024 March 99 (3):408-421. Epub 01/13/2024.

Zhou T, Curry CV, Khanlari M, Shi M, Cui W, Peker D, Chen W, Wang E, Gao J, Shen Q, Xie W, Jelloul FZ, King RL, Yuan J, Wang X, Zhao C, Obiorah IE, Courville EL, Nomura E, Cherian S, Xu ML, Burack WR, Liu HX, Jabbour EJ, Takahashi K, Wang W, Wang SA, Khoury JD, Medeiros LJ, Hu S

Blood cancer journal.. 2024 January 2514 (1):19. Epub 01/25/2024.

Burack WR, Li H, Adlowitz DG, Spence JM, Rimsza LM, Shadman M, Spier C, Kaminski MS, Leonard JP, Leblanc M, Smith SM, Friedberg JW

Blood advances.. 2023 September 127 (17):5082-5090. Epub 1900 01 01.

Burack WR, Lichtman MA

Annals of internal medicine.. 2023 August 176 (8):eL230165. Epub 1900 01 01.

Archibald WJ, Baran AM, Williams AM, Salloum RM, Richard Burack W, Evans AG, Syposs CR, Zent CS

Leukemia research.. 2023 May 128 :107053. Epub 03/02/2023.

Centor RM, Burack WR, Lichtman MA

Annals of internal medicine.. 2023 April 176 (4):eA220007. Epub 04/04/2023.

Burack WR, Lichtman MA

Annals of internal medicine.. 2023 March 176 (3):404-405. Epub 01/31/2023.

El Hussein S, Wang X, Fang H, Jelloul FZ, Wang W, Loghavi S, Vega F, Miranda RN, Muzzafar T, Manning JT, Khoury JD, Burack WR, Evans AG, Medeiros LJ

The American journal of surgical pathology.. 2022 September 146 (9):1291-1297. Epub 05/16/2022.

Liu L, Adlowitz DG, Rock P, Casulo C, Burack WR

Leukemia & lymphoma.. 2022 August 63 (8):2005-2008. Epub 03/31/2022.

El Hussein S, Yabe M, Wang W, Pemmaraju N, Loghavi S, Jelloul FZ, Fang H, Medeiros LJ, Burack WR, Evans AG, Liesveld JL, Bennett JM

EJHaem.. 2022 August 3 (3):954-957. Epub 07/03/2022.

Casulo C, Larson MC, Lunde JJ, Habermann TM, Lossos IS, Wang Y, Nastoupil LJ, Strouse C, Chihara D, Martin P, Cohen JB, Kahl BS, Burack WR, Koff JL, Mun Y, Masaquel A, Wu M, Wei MC, Shewade A, Li J, Cerhan J, Flowers CR, Link BK, Maurer MJ

The Lancet. Haematology.. 2022 April 9 (4):e289-e300. Epub 1900 01 01.

Komisarof J, Lipof J, DiTursi J, Chowdhry A, Grace Choung HY, Burack WR, Constine L, Passero F

Case reports in hematology.. 2022 2022 :7531142. Epub 02/21/2022.

Zengin HB, Reyes-Barron C, Cusick E, Cordisco M, Katzman PJ, Burack WR, Scott G

The American Journal of dermatopathology.. 2021 December 143 (12):e267-e272. Epub 1900 01 01.

Norris PAA, Segel GB, Burack WR, Sachs UJ, Lissenberg-Thunnissen SN, Vidarsson G, Bayat B, Cserti-Gazdewich CM, Callum J, Lin Y, Branch D, Kapur R, Semple JW, Lazarus AH

Haematologica.. 2021 January 1106 (1):250-254. Epub 01/01/2021.

DC-SIGN binding to mannosylated B-cell receptors in follicular lymphoma down-modulates receptor signaling capacity

Valle-Argos B, Chiodin G, Bryant DJ, Taylor J, Lemm E, Duriez PJ, Rock PJ, Strefford JC, Forconi F, Burack RW, Packham G, Stevenson FK.

Sci Rep. 2021; 11(1): 11676.

Musashi 2 influences chronic lymphocytic leukemia cell survival and growth making it a potential therapeutic target

Palacios F, Yan XJ, Ferrer G, Chen SS, Vergani S, Yang X, Gardner J, Barrientos JC, Rock P, Burack R, Kolitz JE, Allen SL, Kharas MG, Abdel-Wahab O, Rai KR, Chiorazzi N.

Leukemia. 2021; 35(4): 1037-52.

Insertion of atypical glycans into the tumor antigen-binding site identifies DLBCLs with distinct origin and behavior

Chiodin G, Allen JD, Bryant D, Rock P, Martino EA, Valle-Argos B, Duriez PJ, Watanabe Y, Henderson I, Blachly JS, McCann KJ, Strefford JC, Packham G, Geijtenbeek TB, Figdor C, Wright G, Staudt LM, Burack R, Bowden T, Crispin M, Stevenson FK, Forconi F.

Blood. 2021; .

Meacham PJ, Williams AM, Strawderman M, Baran AM, Archibald WJ, Wallace DS, Tschernia NP, Burack WR, Barr PM, Zent CS

Leukemia & lymphoma.. 2020 July 61 (7):1636-1644. Epub 03/16/2020.

Fries C, Adlowitz DG, Spence JM, Spence JP, Rock PJ, Burack WR

Pediatric blood & cancer.. 2020 June 67 (6):e28280. Epub 04/11/2020.

Fries C, Burack WR

Leukemia research.. 2018 December 75 :15-22. Epub 11/03/2018.

Hudson CA, Burack WR, Bennett JM

Leukemia research.. 2018 October 73 :12-15. Epub 08/28/2018.

Hudson CA, Burack WR, Leary PC, Bennett JM

American journal of clinical pathology.. 2018 August 30150 (4):293-302. Epub 1900 01 01.

Aslam R, Burack WR, Segel GB, McVey M, Spence SA, Semple JW

British journal of haematology.. 2018 April 181 (2):262-264. Epub 02/06/2017.

Barr PM, Li H, Burack WR, LeBlanc M, Smith SM, Gopal AK, Floyd JD, Persky DO, Press OW, Fisher RI, Friedberg JW

The Lancet. Haematology.. 2018 March 5 (3):e102-e108. Epub 01/26/2018.

Burack WR, Spence JM, Spence JP, Spence SA, Rock PJ, Shenoy GN, Shultz LD, Bankert RB, Bernstein SH

Blood advances.. 2017 July 111 (16):1263-1273. Epub 07/07/2017.

Hunter BD, Herr M, Meacham PJ, Barlaskar F, Evans AG, Burack WR, Liesveld JL, Becker MW, Milner LA, Constine LS, Dhakal S, Barr PM, Friedberg JW, Casulo C

Clinical lymphoma, myeloma & leukemia.. 2017 March 17 (3):145-151. Epub 11/23/2016.

Patel N, Hoffman CM, Goldman BI, Bentley K, Burack WR, Evans AG

Acta haematologica.. 2017 138 (2):85-90. Epub 08/17/2017.

Reyes-Barron C, Burack WR, Rothberg PG, Ding Y

Critical reviews in oncogenesis.. 2017 22 (5-6):559-567. Epub 1900 01 01.

Youn P, Cummings MA, Dhakal S, Burack WR, Casulo C, Barr PM, Friedberg JW, Constine LS

International journal of radiation oncology, biology, physics.. 2016 October 196 (2S):E495. Epub 1900 01 01.

Evans AG, Ahmad A, Burack WR, Iqbal MA

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.. 2016 October 29 (10):1183-99. Epub 07/08/2016.

Redd L, Schmelz M, Burack WR, Cook JR, Day AW, Rimsza L

Journal of hematopathology.. 2016 September 9 (3):107-112. Epub 03/10/2016.

Kuzin II, Kates SL, Ju Y, Zhang L, Rahimi H, Wojciechowski W, Bernstein SH, Burack R, Schwarz EM, Bottaro A

European journal of immunology.. 2016 July 46 (7):1752-7. Epub 05/06/2016.

Aslam R, Segel GB, Burack R, Spence SA, Speck ER, Guo L, Semple JW

British journal of haematology.. 2016 April 173 (1):159-60. Epub 06/24/2015.

Lindorfer MA, Cook EM, Tupitza JC, Zent CS, Burack R, de Jong RN, Beurskens FJ, Schuurman J, Parren PW, Taylor RP

Molecular immunology.. 2016 February 70 :13-23. Epub 12/12/2015.

Till BG, Li H, Bernstein SH, Fisher RI, Burack WR, Rimsza LM, Floyd JD, DaSilva MA, Moore DF, Pozdnyakova O, Smith SM, LeBlanc M, Friedberg JW

British journal of haematology.. 2016 January 172 (2):208-18. Epub 10/22/2015.

Nedelkovska H, Rosenberg AF, Hilchey SP, Hyrien O, Burack WR, Quataert SA, Baker CM, Azadniv M, Welle SL, Ansell SM, Kim M, Bernstein SH

PloS one.. 2016 11 (5):e0155347. Epub 05/26/2016.

Evans AG, Rothberg PG, Burack WR, Huntington SF, Porter DL, Friedberg JW, Liesveld JL

British journal of haematology.. 2015 October 171 (2):205-209. Epub 06/18/2015.

Halliley JL, Tipton CM, Liesveld J, Rosenberg AF, Darce J, Gregoretti IV, Popova L, Kaminiski D, Fucile CF, Albizua I, Kyu S, Chiang KY, Bradley KT, Burack R, Slifka M, Hammarlund E, Wu H, Zhao L, Walsh EE, Falsey AR, Randall TD, Cheung WC, Sanz I, Lee FE

Immunity.. 2015 July 2143 (1):132-45. Epub 07/14/2015.

Pulvino M, Chen L, Oleksyn D, Li J, Compitello G, Rossi R, Spence S, Balakrishnan V, Jordan C, Poligone B, Casulo C, Burack R, Shapiro JL, Bernstein S, Friedberg JW, Deshaies RJ, Land H, Zhao J

Oncotarget.. 2015 June 206 (17):14796-813. Epub 1900 01 01.

Vajpayee N, Burack R, Wang D, Hutchison RE, Gajra A

Clinical lymphoma, myeloma & leukemia.. 2015 March 15 (3):159-63. Epub 10/02/2014.

Frederiksen JK, Sharma M, Casulo C, Burack WR

Archives of pathology & laboratory medicine.. 2015 February 139 (2):245-51. Epub 1900 01 01.

Casulo C, Burack WR, Friedberg JW

Blood.. 2015 January 1125 (1):40-7. Epub 12/11/2014.

Using Flow Cytometry for the Diagnosis of Lung Neuroendocrine Carcinoma With Samples From Endobronchial Ultrasound Fine Needle Aspiration and Pleural Fluid

Journal of Interdisciplinary Histopathology. 2015; 3(1): 3-8.

Spence JM, Spence JP, Abumoussa A, Burack WR

Genome medicine.. 2015 7 (1):24. Epub 03/12/2015.

Zent CS, Burack WR

Hematology. 2014 December 52014 (1):119-24. Epub 11/18/2014.

Spence JM, Abumoussa A, Spence JP, Burack WR

The Journal of immunology : official journal of the American Association of Immunologists.. 2014 November 15193 (10):4888-94. Epub 10/13/2014.

Subik MK, Herr MM, Hutchison RE, Kelly J, Tyler WK, Merzianu M, Burack WR

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.. 2014 November 27 (11):1430-1437. Epub 04/18/2014.

Friedberg JW, Unger JM, Burack WR, Gopal AK, Raju RN, Nademanee AP, Kaminski MS, Li H, Press OW, Miller TP, Fisher RI

British journal of haematology.. 2014 August 166 (3):382-9. Epub 04/18/2014.

Friedberg JW, Mahadevan D, Cebula E, Persky D, Lossos I, Agarwal AB, Jung J, Burack R, Zhou X, Leonard EJ, Fingert H, Danaee H, Bernstein SH

Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2014 January 132 (1):44-50. Epub 09/16/2013.

Brown JT, Burack WR, Becker MW, Vlad-Vonica R, Nadasdy T, Bennett JM, Mendler JH

Leukemia research reports.. 2014 3 (2):49-50. Epub 06/18/2014.

Bernstein SH, Epner E, Unger JM, Leblanc M, Cebula E, Burack R, Rimsza L, Miller TP, Fisher RI

Annals of oncology : official journal of the European Society for Medical Oncology. 2013 June 24 (6):1587-93. Epub 03/15/2013.

Rauh MJ, Rahman F, Good D, Silverman J, Brennan MK, Dimov N, Liesveld J, Ryan DH, Richard Burack W, Bennett JM

Leukemia research.. 2012 January 36 (1):81-6. Epub 09/03/2011.

Yeung CC, Powers ML, Nguyen TD, Kreisel F, Frater JL, Zehnbauer BA, Burack R, Hassan A

International journal of surgical pathology.. 2011 October 19 (5):563-9. Epub 05/01/2011.

Hilchey SP, Rosenberg AF, Hyrien O, Secor-Socha S, Cochran MR, Brady MT, Wang JC, Sanz I, Burack WR, Quataert SA, Bernstein SH

Blood.. 2011 September 29118 (13):3591-602. Epub 08/05/2011.

Spence JM, Rothberg PG, Wang N, Burack WR

The Journal of molecular diagnostics : JMD.. 2011 May 13 (3):252-62. Epub 1900 01 01.

Amador-Ortiz C, Chen L, Hassan A, Frater JL, Burack R, Nguyen TT, Kreisel F

American journal of clinical pathology.. 2011 April 135 (4):516-24. Epub 1900 01 01.

Cooper AR, Burack WR, Allerton JP

Leukemia & lymphoma.. 2010 December 51 (12):2303-5. Epub 10/07/2010.

Ferrantino M, Eichelberger J, Burack HR, Li F, Lee FE

Chest.. 2010 November 138 (5):1260-4. Epub 1900 01 01.

Bennett JM, Pryor J, Laughlin TS, Rothberg PG, Burack WR

American journal of clinical pathology.. 2010 October 134 (4):648-52. Epub 1900 01 01.

Burack WR, Laughlin TS, Friedberg JW, Spence JM, Rothberg PG

American journal of clinical pathology.. 2010 July 134 (1):104-11. Epub 1900 01 01.

Hilchey SP, Kobie JJ, Cochran MR, Secor-Socha S, Wang JC, Hyrien O, Burack WR, Mosmann TR, Quataert SA, Bernstein SH

The Journal of immunology : official journal of the American Association of Immunologists.. 2009 November 15183 (10):6157-66. Epub 10/28/2009.

Bernstein SH, Burack WR

Hematology. 2009 :532-41. Epub 1900 01 01.

Vomastek T, Iwanicki MP, Burack WR, Tiwari D, Kumar D, Parsons JT, Weber MJ, Nandicoori VK

Molecular and cellular biology.. 2008 November 28 (22):6954-66. Epub 09/15/2008.

Halldórsdóttir AM, Frühwirth M, Deutsch A, Aigelsreiter A, Beham-Schmid C, Agnarsson BA, Neumeister P, Richard Burack W

Leukemia research.. 2008 July 32 (7):1015-21. Epub 01/04/2008.

Halldórsdóttir AM, Zehnbauer BA, Burack WR

Leukemia & lymphoma.. 2007 July 48 (7):1338-43. Epub 1900 01 01.

Seo J, Chung YS, Sharma GG, Moon E, Burack WR, Pandita TK, Choi K

Oncogene.. 2005 December 824 (55):8176-86. Epub 1900 01 01.

Markiewicz MA, Carayannopoulos LN, Naidenko OV, Matsui K, Burack WR, Wise EL, Fremont DH, Allen PM, Yokoyama WM, Colonna M, Shaw AS

The Journal of immunology : official journal of the American Association of Immunologists.. 2005 September 1175 (5):2825-33. Epub 1900 01 01.

Tu PH, Giannini C, Judkins AR, Schwalb JM, Burack R, O'Neill BP, Yachnis AT, Burger PC, Scheithauer BW, Perry A

Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2005 August 2023 (24):5718-27. Epub 07/11/2005.

Burack WR, Shaw AS

The Journal of biological chemistry.. 2005 February 4280 (5):3832-7. Epub 11/16/2004.

Lee KH, Dinner AR, Tu C, Campi G, Raychaudhuri S, Varma R, Sims TN, Burack WR, Wu H, Wang J, Kanagawa O, Markiewicz M, Allen PM, Dustin ML, Chakraborty AK, Shaw AS

Science.. 2003 November 14302 (5648):1218-22. Epub 09/25/2003.

Burack WR, Lee KH, Holdorf AD, Dustin ML, Shaw AS

The Journal of immunology : official journal of the American Association of Immunologists.. 2002 September 15169 (6):2837-41. Epub 1900 01 01.

Hailman E, Burack WR, Shaw AS, Dustin ML, Allen PM

Immunity.. 2002 June 16 (6):839-48. Epub 1900 01 01.

Nguyen A, Burack WR, Stock JL, Kortum R, Chaika OV, Afkarian M, Muller WJ, Murphy KM, Morrison DK, Lewis RE, McNeish J, Shaw AS

Molecular and cellular biology.. 2002 May 22 (9):3035-45. Epub 1900 01 01.

Holdorf AD, Lee KH, Burack WR, Allen PM, Shaw AS

Nature immunology.. 2002 March 3 (3):259-64. Epub 02/04/2002.

Burack WR, Dibble AR, Biltonen RL

Chemistry and physics of lipids.. 1997 November 1990 (1-2):87-95. Epub 1900 01 01.

Burack WR, Dibble AR, Allietta MM, Biltonen RL

Biochemistry.. 1997 August 2636 (34):10551-7. Epub 1900 01 01.

Burack WR, Sturgill TW

Biochemistry.. 1997 May 2036 (20):5929-33. Epub 1900 01 01.

Burack WR, Gadd ME, Biltonen RL

Biochemistry.. 1995 November 1434 (45):14819-28. Epub 1900 01 01.

Burack WR, Biltonen RL

Chemistry and physics of lipids.. 1994 September 673 (1-2):209-22. Epub 1900 01 01.

Burack WR, Yuan Q, Biltonen RL

Biochemistry.. 1993 January 1932 (2):583-9. Epub 1900 01 01.

Lathrop BK, Burack WR, Biltonen RL, Rule GS

Protein expression and purification.. 1992 December 3 (6):512-7. Epub 1900 01 01.

Books

Molecular Pathology of Hematolymphoid Disease (2010)

Chapter: The Roles of Molecular Techniques in the Diagnosis and Management of Follicular Lymphoma

Authors: W. Richard Burack

Publisher: Springer 2010

Translational and Experimental Clinical Research (2005)

Chapter: Non-imaging Cell and Tissue Techniques and Tissue Banking

Authors: W. Richard Burack John D. Pfeifer

Publisher: Lippincott Williams and Wilkins, Philadelphia, PA 2005

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