Jin Xiao, D.D.S., Ph.D.

Jin Xiao, DDS, PhD, is an Associate Professor and the Founding Director of Perinatal Oral Health at the �鶹��Ƶ's Eastman Institute for Oral Health. She leads the pioneering Eastman Dental Pregnancy and Infant Oral Health Program, which delivers comprehensive oral health services to pregnant women and their young children. Dr. Xiao also serves as the Associate Director of the KL2 Career Development Program at the University of Rochester's Clinical and Translational Science Institute. Her leadership extends to international scientific organizations, where she holds key roles such as President-Elect of the International Association for Dental Research (IADR) e-Oral Health Network, President of the IADR Clinical and Translational Science Network. She also serves as the Scientific Councilor of the American Dental Association. The prestigious Council is comprised of about 20 renowned U.S. oral health researchers and clinicians who assist the ADA in developing policies that sustain the science basis of the dental profession, while supporting product standards and evaluation, research priorities, safety and efficacy of patient procedures, the ADA Seal of Acceptance Program and much more.

Dr. Xiao earned her DDS and completed her specialty training in endodontics at the West China College of Stomatology, Sichuan University. She pursued a joint PhD in oral microbiology at the West China College of Stomatology and completed the last two years of training at the Eastman Institute for Oral Health. Her postgraduate training includes an Advanced Education in General Dentistry residency at the Eastman Institute for Oral Health and a General Practice residency at Strong Memorial Hospital, �鶹��Ƶ.

Dr. Xiao conducts a full spectrum of translational research to promote maternal and child oral health and establish oral health equity at birth in underserved communities. Her research expertise includes maternal and infant oral health clinical and translational research, mDentistry, oral microbiome, and cross-kingdom bacteria and yeast interaction in dental caries. As a principal investigator of NIH- and NSF-funded clinical and translational studies, Dr. Xiao leads initiatives such as the Oral Microbiome in Early Infancy (OMEI) project, which investigates the role of oral Candida in early childhood caries, maternal transmission of cariogenic microorganisms, and the impact of oral pathogens on children's health. She also spearheads the AICaries and SMARTeeth projects, which utilize AI-powered smartphone technology and community engagement strategies to improve access to care and promote early detection and prevention of oral disease.

Mentorship has been a fundamental aspect of Dr. Xiao's academic career. She has provided mentorship to over 50 mentees, encompassing junior faculty, postdoctoral dental residents, PhD, master’s, and undergraduate students. A significant number of her mentees are women or individuals from minority backgrounds, many of whom have advanced to dental school faculty positions.

Languages

English, Chinese

Faculty Appointments

Associate Professor - Department of Dentistry (SMD)

Credentials

Residency & Fellowship

Residency, General Practice, Eastman Dental Center. 2013 - 2014

Residency, Dentistry, General Practice, Eastman Dental Center. 2010 - 2013

Education

PHD | West China College of Stomatology (China). 2009

DDS | West China College of Stomatology (China). 2005

Awards

American Society for Microbiology Candida and Candidiasis conference travel award. 2018

First Place of Johnson & Johnson Hatton Award Competition (Senior Category). 2011

First Place of William H. Bowen Award Competition. 2010

Outstanding Young Researcher to attend The Nobel Laureate Meetings at Lindau, Germany. 2007

The USA 100-Committee Scholarship. 2007

The Second Prize in the DENTSPLY Asia/China Dental Student Clinician Competition. 2006

Research

Jin Xiao, DDS, PhD, is an Associate Professor and the Founding Director of Perinatal Oral Health at the �鶹��Ƶ's Eastman Institute for Oral Health. She leads the pioneering Eastman Dental Pregnancy and Infant Oral Health Program, which delivers comprehensive oral health services to pregnant women and their young children. Dr. Xiao also serves as the Associate Director of the KL2 Career Development Program at the University of Rochester's Clinical and Translational Science Institute. Her leadership extends to international scientific organizations, where she holds key roles such as President-Elect of the International Association for Dental Research (IADR) e-Oral Health Network and President of the IADR Clinical and Translational Science Network. She also serves as the Scientific Councilor of the American Dental Association. The prestigious Council is comprised of about 20 renowned U.S. oral health researchers and clinicians who assist the ADA in developing policies that sustain the science basis of the dental profession while supporting product standards and evaluation, research priorities, safety and efficacy of patient procedures, the ADA Seal of Acceptance Program and much more.

Dr. Xiao earned her DDS and completed her specialty training in endodontics at the West China College of Stomatology, Sichuan University. She pursued a joint PhD in oral microbiology at the West China College of Stomatology and completed the last two years of training at the Eastman Institute for Oral Health. Her postgraduate training includes an Advanced Education in General Dentistry residency at the Eastman Institute for Oral Health and a General Practice residency at Strong Memorial Hospital, �鶹��Ƶ.

Dr. Xiao conducts a full spectrum of translational research to promote maternal and child oral health and establish oral health equity at birth in underserved communities. Her research expertise includes maternal and infant oral health clinical and translational research, mDentistry, oral microbiome, and cross-kingdom bacteria and yeast interaction in dental caries. As a principal investigator of NIH- and NSF-funded clinical and translational studies, Dr. Xiao leads initiatives such as the Oral Microbiome in Early Infancy (OMEI) project, which investigates the role of oral Candida in early childhood caries, maternal transmission of cariogenic microorganisms, and the impact of oral pathogens on children's health. She also spearheads the AICaries and SMARTeeth projects, which utilize AI-powered smartphone technology and community engagement strategies to improve access to care and promote early detection and prevention of oral disease.

Mentorship has been a fundamental aspect of Dr. Xiao's academic career. She has mentored over 50 mentees, encompassing junior faculty, postdoctoral dental residents, PhD, master's, and undergraduate students. Many of her mentees are women or individuals from minority backgrounds, many of whom have advanced to dental school faculty positions.

Publications

Journal Articles

Aljohani A, Rashwan N, Vasani S, Alkhawashki A, Wu TT, Lu X, Castillo DA, Xiao J

Probiotics and antimicrobial proteins.. 2024 May 31 Epub 05/31/2024.

Yang R, Lu X, Alomeir N, Quataert S, Wu T, Xiao J

Journal of clinical medicine.. 2024 May 2913 (11)Epub 05/29/2024.

Cui S, Fiscella K, Xiao J

Quintessence international.. 2024 April 2555 (4):262-263. Epub 1900 01 01.

Alkadi A, Alkhars N, Manning S, Xu H, Sohn M, Xiao J, Meng Y

Nutrients.. 2024 April 1016 (8)Epub 04/10/2024.

Yousif D; Wu Y; Gonzales A; Mathieu C; Zeng Y; Lee S; Terando S; Li T; Xiao J.

Pharmaceutics. 2024; 16(2): 215.

Alkhars N, Al Jallad N, Wu TT, Xiao J

PloS one.. 2024 19 (1):e0290938. Epub 01/17/2024.

Gilbert Klaczko C, Alkhars N, Zeng Y, Klaczko ME, Gill AL, Kopycka-Kedzierawski DT, Jusko TA, Sohn MB, Xiao J, Gill SR

Journal of dental research.. 2023 September 102 (10):1122-1130. Epub 07/11/2023.

Xiao J, Kopycka-Kedzierawski D, Ragusa P, Mendez Chagoya LA, Funkhouser K, Lischka T, Wu TT, Fiscella K, Kar KS, Al Jallad N, Rashwan N, Ren J, Meyerowitz C,

JMIR human factors.. 2023 August 1810 :e45418. Epub 08/18/2023.

Aljaffary M, Jang H, Alomeir N, Zeng Y, Alkhars N, Vasani S, Almulhim A, Wu TT, Quataert S, Bruno J, Lee A, Xiao J

Clinical oral investigations.. 2023 July 27 (7):3557-3568. Epub 03/24/2023.

Bao J, Huang X, Zeng Y, Wu TT, Lu X, Meng G, Ren Y, Xiao J

Pathogens.. 2023 June 2012 (6)Epub 06/20/2023.

Assery N, Alomeir N, Zeng Y, Xiao J, Tsigarida A

Journal of periodontology.. 2023 March 94 (3):344-353. Epub 12/07/2022.

Zeng Y, Fadaak A, Alomeir N, Wu Y, Wu TT, Qing S, Xiao J

International journal of molecular sciences.. 2023 February 324 (3)Epub 02/03/2023.

Fan Y, Lyu H, Xiao J, Luo J

Quintessence international.. 2023 January 1354 (1):64-76. Epub 1900 01 01.

Alomeir N, Zeng Y, Fadaak A, Wu TT, Malmstrom H, Xiao J

Archives of oral biology.. 2023 January 145 :105582. Epub 11/09/2022.

Samantha Manning, Jin Xiao, Yihong Li, Prakaimuk Saraithong, Bruce J. Paster, George Chen, Yan Wu, and Tong Tong Wu.

Genes. 2023; 14(3): 641.

Tong Tong Wu, Michael Sohn, Samantha Manning, Robert Beblavy, Steven Gill, Sally Quataert, Shruti Vasani, Hoonji Jang, Yan Zeng, Jennifer Bruno, Adriana Vazquez, Kevin Fiscella, Jin Xiao.

Journal of Translational Medicine. 2023; 21: 172.

Dynamics of Oral Microbiome Acquisition in Healthy Infants: A Pilot Study

YIHONG Li, Prakaimuk Saraithong, Lanxin Zhang, Ashley Dills, Bruce J. Paster, Jin Xiao, Tong Tong Wu and Zachary Jones.

Front. Oral. Health. 2023; 4.

Huang XY, Bao JH, Zeng Y, Meng G, Lu XY, Wu TT, Ren YF, Xiao J.

Nutrients. 2023; 15(9): 2017.

Zhang, L; Manning, S; Wu, TT; Zeng, Y; Lee, L; Wu, Y; Paster, B; Chen, G; Fiscella, K; Xiao J.

Microorganisms. 2023; 11(6): 1497.

Xiao J, Zeng Y, Rustchenko E, Huang X, Wu TT, Falsetta ML

Journal of oral microbiology.. 2023 15 (1):2144047. Epub 11/09/2022.

Kalenderian E, White J, Yansane AI, Urata J, Holmes D, Funkhouser K, Mungia R, Xiao J, Rauschenberger C, Ibarra-Noriega A, Tran D, Rindal DB, Spallek H, Walji M

BMC oral health.. 2022 December 922 (1):581. Epub 12/09/2022.

Al Jallad N, Vasani S, Wu TT, Cacciato R, Thomas M, Lababede N, Lababede A, Xiao J

Quintessence international.. 2022 October 2153 (10):892-902. Epub 1900 01 01.

Ren Z, Jeckel H, Simon-Soro A, Xiang Z, Liu Y, Cavalcanti IM, Xiao J, Tin NN, Hara A, Drescher K, Koo H

Proceedings of the National Academy of Sciences of the United States of America.. 2022 October 11119 (41):e2209699119. Epub 10/03/2022.

Yan Zeng, Ahmed Fadaak, Nora Alomeir, Tong Tong Wu, Elena Rustchenko, Shuang Qing, Jianhang Bao, Christie Gilbert, Jin Xiao.

Frontiers in Cellular and Infection Microbiology. 2022; .

Wu TT, Xiao J, Manning S, Saraithong P, Pattanaporn K, Paster BJ, Chen T, Vasani S, Gilbert C, Zeng Y, Li Y.

Frontiers in Cellular and Infectious Microbiology. 2022; .

Artificial intelligence-powered smartphone application, AICaries, improves at-home dental caries screening in children: Moderated and unmoderated usability test.

Al Jallad N, Mapes O, Hao P, Ruan J, Ramesh A, Luo J, Wu T, Dye T, Rashwan N, Ren J, Jang H, Mendez L, Alomier N, Bullock S, Fiscella K, Xiao J.

PLOS digital health. 2022 June. 2022; .

Editorial: The Pivotal Role of Oral Microbiota Dysbiosis and Microbiota-Host Interactions in Diseases

Xin Xu , Jin Xiao, Yulong Niu.

Front. Cell. Infect. Microbiol. 2022; .

Xiao J, Meyerowitz C, Ragusa P, Funkhouser K, Lischka T, Mendez Chagoya LA, Al Jallad N, Wu TT, Fiscella K, Ivie E, Strange M, Collins J, Kopycka-Kedzierawsk DT

JMIR research protocols.. 2021 October 2610 (10):e32345. Epub 10/26/2021.

Alzamil H, Wu TT, van Wijngaarden E, Mendoza M, Malmstrom H, Fiscella K, Kopycka-Kedzierawski DT, Billings RJ, Xiao J

JDR clinical and translational research.. 2021 October 238 (1):23800844211049406. Epub 10/23/2021.

Xiao J, Luo J, Ly-Mapes O, Wu TT, Dye T, Al Jallad N, Hao P, Ruan J, Bullock S, Fiscella K

JMIR research protocols.. 2021 October 2210 (10):e32921. Epub 10/22/2021.

Jang H, Patoine A, Wu TT, Castillo DA, Xiao J

Scientific reports.. 2021 August 1911 (1):16870. Epub 08/19/2021.

Jang H, Al Jallad N, Wu TT, Zeng Y, Fadaak A, Malmstrom H, Fiscella K, Xiao J

Heliyon.. 2021 August 7 (8):e07871. Epub 08/26/2021.

Alkhars N, Zeng Y, Alomeir N, AlJallad N, Wu TT, Aboelmagd S, Youssef M, Jang H, Fogarty C, Xiao J.

Journal of Dental Research. 2021; .

Xiao, J; Fiscella K; Meyerowitz, C.

Journal of American Dental Association. 2021; .

(2021) Early Childhood Caries Experience Associated with Upper Respiratory Infection in US Children: Findings from a Retrospective Cohort Study.

Albelali, A, Wu, TT, Malmstrom, H, and Xiao, J.

Journal of Pediatrics & Child Health Care. 2021; 6(2): 1044.

Wu TT, Xiao J, Sohn MB, Fiscella KA, Gilbert C, Grier A, Gill AL, Gill SR

Frontiers in cellular and infection microbiology.. 2021 11 :727630. Epub 08/19/2021.

Identification of Non- Streptococcus mutans Bacteria from Predente Infant Saliva Grown on Mitis-Salivarius-Bacitracin Agar

Zeng Y, Youssef M, Wang L, Alkhars N, Thomas M, Cacciato R, Qing S, Ly-Mapes O, Xiao J.

J Clin Pediatr Dent. 2020; 44(1): 28-34.

Jin Xiao; Kevin A. Fiscella; Steven R. Gill.

international journal of oral science. 2020; .

Lin Wang, Johana Ren, Kevin A Fiscella, Sherita Bullock, Mechelle R Sanders, Elizabeth L Loomis, Eli Eliav, Michael Mendoza, Rita Cacciato, Marie Thomas, Dorota T Kopycka-Kedzierawski, Ronald J Billings, Jin Xiao.

2020; .

Zhang Y, Liao H, Xiao J, Al Jallad N, Ly-Mapes O, Luo J.

2020; .

Xiao J, Fogarty C, Wu TT, Alkhers N, Zeng Y, Thomas M, Youssef M, Wang L, Cowen L, Abdelsalam H, Nikitkova A

BMC pregnancy and childbirth.. 2019 December 519 (1):480. Epub 12/05/2019.

Billings RJ, Kopycka-Kedzierawski DT, Xiao J

The Journal of the American Dental Association.. 2019 July 150 (7):565-566. Epub 1900 01 01.

Meng Y, Wu T, Billings R, Kopycka-Kedzierawski DT, Xiao J

International journal of oral science.. 2019 May 3011 (2):19. Epub 05/30/2019.

Zeng Y, Nikitkova A, Abdelsalam H, Li J, Xiao J

Archives of oral biology.. 2019 February 98 :9-16. Epub 11/02/2018.

Xiao J, Alkhers N, Kopycka-Kedzierawski DT, Billings RJ, Wu TT, Castillo DA, Rasubala L, Malmstrom H, Ren Y, Eliav E

Caries research.. 2019 53 (4):411-421. Epub 01/10/2019.

Kopycka-Kedzierawski DT, Li D, Xiao J, Billings RJ, Dye TD

PloS one.. 2019 14 (4):e0215440. Epub 04/18/2019.

Xiao J, Grier A, Faustoferri RC, Alzoubi S, Gill AL, Feng C, Liu Y, Quivey RG, Kopycka-Kedzierawski DT, Koo H, Gill SR

Journal of dental research.. 2018 December 97 (13):1468-1476. Epub 07/26/2018.

Xiao J, Huang X, Alkhers N, Alzamil H, Alzoubi S, Wu TT, Castillo DA, Campbell F, Davis J, Herzog K, Billings R, Kopycka-Kedzierawski DT, Hajishengallis E, Koo H

Caries research.. 2018 52 (1-2):102-112. Epub 12/21/2017.

Xiao J, Hara AT, Kim D, Zero DT, Koo H, Hwang G

International journal of oral science.. 2017 June 9 (2):74-79. Epub 04/28/2017.

Xiao J, Moon Y, Li L, Rustchenko E, Wakabayashi H, Zhao X, Feng C, Gill SR, McLaren S, Malmstrom H, Ren Y, Quivey R, Koo H, Kopycka-Kedzierawski DT

PloS one.. 2016 11 (10):e0164242. Epub 10/14/2016.

Malmstrom H, Dellanzo-Savu A, Xiao J, Feng C, Jabeen A, Romero M, Huang J, Ren Y, Yunker MA

Journal of oral rehabilitation.. 2015 December 42 (12):906-13. Epub 07/14/2015.

Malmstrom HS, Xiao J, Romanos G, Ren YF

The Journal of oral implantology.. 2015 June 41 (3):268-75. Epub 11/04/2013.

Training needs for novice general dentists to place and restore two-implant retained mandibular overdentures

Malmstrom H, Xiao J, Romanos G, Ren YF.

Journal of Dental Education. 2014; .

Guan X, Zhou Y, Liang X, Xiao J, He L, Li J

Microbiological research.. 2012 January 20167 (2):61-8. Epub 04/17/2011.

Xiao J, Klein MI, Falsetta ML, Lu B, Delahunty CM, Yates JR, Heydorn A, Koo H

PLoS pathogens.. 2012 8 (4):e1002623. Epub 04/05/2012.

Klein MI, Xiao J, Lu B, Delahunty CM, Yates JR, Koo H

PloS one.. 2012 7 (9):e45795. Epub 09/25/2012.

Gregoire S, Xiao J, Silva BB, Gonzalez I, Agidi PS, Klein MI, Ambatipudi KS, Rosalen PL, Bauserman R, Waugh RE, Koo H

Applied and environmental microbiology.. 2011 September 77 (18):6357-67. Epub 07/29/2011.

Jeon JG, Pandit S, Xiao J, Gregoire S, Falsetta ML, Klein MI, Koo H

International journal of oral science.. 2011 April 3 (2):98-106. Epub 1900 01 01.

Klein MI, Xiao J, Heydorn A, Koo H

Journal of visualized experiments : JoVE.. 2011 January 25 (47)Epub 01/25/2011.

Xiao J, Koo H

Journal of applied microbiology.. 2010 June 108 (6):2103-13. Epub 11/04/2009.

Koo H, Xiao J, Klein MI, Jeon JG

Journal of bacteriology.. 2010 June 192 (12):3024-32. Epub 03/16/2010.

Zhu WC, Xiao J, Liu Y, Wu J, Li JY

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association.. 2010 January 47 (1):43-7. Epub 1900 01 01.

Jeon JG, Klein MI, Xiao J, Gregoire S, Rosalen PL, Koo H

BMC microbiology.. 2009 October 289 :228. Epub 10/28/2009.

Klein MI, Duarte S, Xiao J, Mitra S, Foster TH, Koo H

Applied and environmental microbiology.. 2009 February 75 (3):837-41. Epub 11/21/2008.

Extracellular polysaccharides matrix--an often forgotten virulence factor in oral biofilm research.

Koo H, Xiao J, Klein MI.

Int J Oral Sci. 2009; 1(4): 229-34.

Xiao J, Zhou XD, Feng J, Hao YQ, Li JY

Letters in applied microbiology.. 2007 November 45 (5):547-52. Epub 10/04/2007.

Xiao J, Zuo Y, Liu Y, Li J, Hao Y, Zhou X

Archives of oral biology.. 2007 September 52 (9):869-75. Epub 03/23/2007.

Xiao J, Zhou XD, Zhu WC, Zhang B, Li JY, Xu X

Journal of oral rehabilitation.. 2007 May 34 (5):351-60. Epub 1900 01 01.

Xiao J, Liu Y, Zuo YL, Li JY, Ye L, Zhou XD

Archives of oral biology.. 2006 September 51 (9):804-13. Epub 05/24/2006.

Books

Designing Bioactive Polymeric Materials For Restorative Dentistry (2020)

Chapter: Nanotechnology and Delivery System for Bioactive Antibiofilm Dental Materials

Authors: Jin Xiao, Yuan Liu, Marlise I. Klein, Anna Nikikova, Yanfang Ren

Publisher: Taylor & Francis Group 2020

Stress and Environmental Regulation of Gene Expression and Adaptation in Bacteria. (2016)

Chapter: Acid-adaptive responses of Streptococcus mutans, and mechanisms of integration with oxidative stress.

Authors: Quivey G, Faustoferri R, Santiago B, Baker J, Cross B, Xiao J

Publisher: Wiley-Blackwell 2016

Oral Microbial Ecology: Current Research and New Perspectives. (2013)

Chapter: The Role of Extracellular Polysaccharides Matrix in Virulent Oral biofilms

Authors: Klein MI, Falsetta ML, Xiao J, Bowen WH, Koo H

Publisher: Cambs UK, Caister Academic Press 2013

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