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Paula M. Vertino, Ph.D.

Paula M. Vertino, Ph.D.

Contact

About Me

Faculty Appointments

Professor - Department of Biomedical Genetics (SMD)

Wilmot Distinguished Professorship in Cancer Genomics - Cancer Center

Senior Associate Dean, Basic Research - Dean's Office M&D - Administration (SMD)

Professor - Department of Pathology and Laboratory Medicine (SMD) - Joint

Research

Dr. Vertino's research interests are focused on the areas of cancer epigenetics and novel mechanisms of gene silencing in cancer.
Dr. Vertino's research interests are focused on the areas of cancer epigenetics and novel mechanisms of gene silencing in cancer.

Publications

Journal Articles

Arana-Chicas E, Lin PJ, Gada U, Sun H, Chakrabarti A, Mattick LJ, Rieth K, Chay CH, Ruzich J, Esparaz BT, Cupertino AP, Altman BJ, Vertino PM, Mohile SG, Mustian KM

Journal of geriatric oncology.. 2024 October 415 (8):102076. Epub 10/04/2024.

Cinar M, Martinez-Medina L, Puvvula PK, Arakelyan A, Vardarajan BN, Anthony N, Nagaraju GP, Park D, Feng L, Sheff F, Mosunjac M, Saxe D, Flygare S, Alese OB, Kaufman JL, Lonial S, Sarmiento JM, Lossos IS, Vertino PM, Lopez JA, El-Rayes B, Bernal-Mizrachi L

Nucleic acids research.. 2024 July 2252 (13):7539-7555. Epub 1900 01 01.

Guo B, Friedland SC, Alexander W, Myers JA, Wang W, O'Dell MR, Getman M, Whitney-Miller CL, Agostini-Vulaj D, Huber AR, Mello SS, Vertino PM, Land HK, Steiner LA, Hezel AF

Cell reports.. 2022 August 3040 (9):111253. Epub 1900 01 01.

Casciello F, Kelly GM, Ramarao-Milne P, Kamal N, Stewart TA, Mukhopadhyay P, Kazakoff SH, Miranda M, Kim D, Davis FM, Hayward NK, Vertino PM, Waddell N, Gannon F, Lee JS

Cancer research.. 2022 April 182 (7):1208-1221. Epub 1900 01 01.

Ruff GL, Murphy KE, Smith ZR, Vertino PM, Murphy PJ

BMC cancer.. 2021 December 1821 (1):1342. Epub 12/18/2021.

Barwick BG, Gupta VA, Matulis SM, Patton JC, Powell DR, Gu Y, Jaye DL, Conneely KN, Lin Y, Hofmeister CC, Nooka AK, Keats JJ, Lonial S, Vertino PM, Boise LH

Clinical cancer research : an official journal of the American Association for Cancer Research.. 2021 June 127 (11):3178-3189. Epub 03/17/2021.

Kim H, Kang Y, Li Y, Chen L, Lin L, Johnson ND, Zhu D, Robinson MH, McSwain L, Barwick BG, Yuan X, Liao X, Zhao J, Zhang Z, Shu Q, Chen J, Allen EG, Kenney AM, Castellino RC, Van Meir EG, Conneely KN, Vertino PM, Jin P, Li J

Genome biology.. 2021 April 2922 (1):125. Epub 04/29/2021.

Zhang B, Li Y, Wu Q, Xie L, Barwick B, Fu C, Li X, Wu D, Xia S, Chen J, Qian WP, Yang L, Osunkoya AO, Boise L, Vertino PM, Zhao Y, Li M, Chen HR, Kowalski J, Kucuk O, Zhou W, Dong JT

Nature communications.. 2021 March 1712 (1):1714. Epub 03/17/2021.

Miyauchi T, Takahashi M, Mitsuzuka K, Saiki Y, Okubo T, Vertino PM, Goto A, Arai Y, Horii A, Fukushige S

Disease markers.. 2021 2021 :8858905. Epub 02/04/2021.

Pedro B, Rupji M, Dwivedi B, Kowalski J, Konen JM, Owonikoko TK, Ramalingam SS, Vertino PM, Marcus AI

Cancer.. 2020 July 1126 (13):3140-3150. Epub 04/21/2020.

Summerbell ER, Mouw JK, Bell JSK, Knippler CM, Pedro B, Arnst JL, Khatib TO, Commander R, Barwick BG, Konen J, Dwivedi B, Seby S, Kowalski J, Vertino PM, Marcus AI

Science advances.. 2020 July 6 (30):eaaz6197. Epub 07/24/2020.

Zoeller EL, Pedro B, Konen J, Dwivedi B, Rupji M, Sundararaman N, Wang L, Horton JR, Zhong C, Barwick BG, Cheng X, Martinez ED, Torres MP, Kowalski J, Marcus AI, Vertino PM

Journal of cell science.. 2019 October 9132 (19)Epub 10/09/2019.

Barwick BG, Neri P, Bahlis NJ, Nooka AK, Dhodapkar MV, Jaye DL, Hofmeister CC, Kaufman JL, Gupta VA, Auclair D, Keats JJ, Lonial S, Vertino PM, Boise LH

Nature communications.. 2019 April 2310 (1):1911. Epub 04/23/2019.

Barwick BG, Gupta VA, Vertino PM, Boise LH

Frontiers in immunology.. 2019 10 :1121. Epub 05/21/2019.

Horton JR, Woodcock CB, Chen Q, Liu X, Zhang X, Shanks J, Rai G, Mott BT, Jansen DJ, Kales SC, Henderson MJ, Cyr M, Pohida K, Hu X, Shah P, Xu X, Jadhav A, Maloney DJ, Hall MD, Simeonov A, Fu H, Vertino PM, Cheng X

Journal of medicinal chemistry.. 2018 December 1361 (23):10588-10601. Epub 11/15/2018.

Kennedy EM, Powell DR, Li Z, Bell JSK, Barwick BG, Feng H, McCrary MR, Dwivedi B, Kowalski J, Dynan WS, Conneely KN, Vertino PM

Scientific reports.. 2018 April 308 (1):6709. Epub 04/30/2018.

Horton JR, Liu X, Wu L, Zhang K, Shanks J, Zhang X, Rai G, Mott BT, Jansen DJ, Kales SC, Henderson MJ, Pohida K, Fang Y, Hu X, Jadhav A, Maloney DJ, Hall MD, Simeonov A, Fu H, Vertino PM, Yan Q, Cheng X

Journal of medicinal chemistry.. 2018 April 1261 (7):3193-3208. Epub 03/23/2018.

Bell JSK, Vertino PM

Epigenetics.. 2017 June 312 (6):449-464. Epub 04/27/2017.

Wang D, Hashimoto H, Zhang X, Barwick BG, Lonial S, Boise LH, Vertino PM, Cheng X

Nucleic acids research.. 2017 March 1745 (5):2396-2407. Epub 1900 01 01.

Horton JR, Liu X, Gale M, Wu L, Shanks JR, Zhang X, Webber PJ, Bell JSK, Kales SC, Mott BT, Rai G, Jansen DJ, Henderson MJ, Urban DJ, Hall MD, Simeonov A, Maloney DJ, Johns MA, Fu H, Jadhav A, Vertino PM, Yan Q, Cheng X

Cell chemical biology.. 2016 July 2123 (7):769-781. Epub 07/14/2016.

Scott EC, Gardner EJ, Masood A, Chuang NT, Vertino PM, Devine SE

Genome research.. 2016 June 26 (6):745-55. Epub 05/10/2016.

Kowalski J, Dwivedi B, Newman S, Switchenko JM, Pauly R, Gutman DA, Arora J, Gandhi K, Ainslie K, Doho G, Qin Z, Moreno CS, Rossi MR, Vertino PM, Lonial S, Bernal-Mizrachi L, Boise LH

Nucleic acids research.. 2016 April 2044 (7):e69. Epub 01/29/2016.

Bell JS, Kagey JD, Barwick BG, Dwivedi B, McCabe MT, Kowalski J, Vertino PM

Epigenetics.. 2016 April 211 (4):273-87. Epub 04/15/2016.

Horton JR, Engstrom A, Zoeller EL, Liu X, Shanks JR, Zhang X, Johns MA, Vertino PM, Fu H, Cheng X

The Journal of biological chemistry.. 2016 February 5291 (6):2631-46. Epub 12/08/2015.

Kellner WA, Bell JS, Vertino PM

Genome research.. 2015 November 25 (11):1600-9. Epub 08/14/2015.

Brodie SA, Li G, Harvey D, Khuri FR, Vertino PM, Brandes JC

Oncotarget.. 2015 October 136 (31):30773-86. Epub 1900 01 01.

Hashimoto H, Zhang X, Vertino PM, Cheng X

The Journal of biological chemistry.. 2015 August 21290 (34):20723-20733. Epub 07/07/2015.

Farkas AE, Hilgarth RS, Capaldo CT, Gerner-Smidt C, Powell DR, Vertino PM, Koval M, Parkos CA, Nusrat A

The American journal of pathology.. 2015 August 185 (8):2206-18. Epub 1900 01 01.

Stoyanov E, Ludwig G, Mizrahi L, Olam D, Schnitzer-Perlman T, Tasika E, Sass G, Tiegs G, Jiang Y, Nie T, Kohler J, Schinazi RF, Vertino PM, Cedar H, Galun E, Goldenberg D

Oncotarget.. 2015 May 106 (13):11047-60. Epub 1900 01 01.

Lin Y, Cradick TJ, Brown MT, Deshmukh H, Ranjan P, Sarode N, Wile BM, Vertino PM, Stewart FJ, Bao G

Nucleic acids research.. 2014 June 42 (11):7473-85. Epub 05/16/2014.

Smith AK, Conneely KN, Pace TW, Mister D, Felger JC, Kilaru V, Akel MJ, Vertino PM, Miller AH, Torres MA

Brain, behavior, and immunity.. 2014 May 38 :227-36. Epub 02/28/2014.

Kapoor-Vazirani P, Vertino PM

The Journal of biological chemistry.. 2014 March 14289 (11):7425-37. Epub 01/23/2014.

Brodie SA, Li G, El-Kommos A, Kang H, Ramalingam SS, Behera M, Gandhi K, Kowalski J, Sica GL, Khuri FR, Vertino PM, Brandes JC

Cancer prevention research.. 2014 March 7 (3):351-61. Epub 01/17/2014.

Brodie SA, Lombardo C, Li G, Kowalski J, Gandhi K, You S, Khuri FR, Marcus A, Vertino PM, Brandes JC

PloS one.. 2014 9 (9):e107124. Epub 09/15/2014.

Yang R, Chen L, Newman S, Gandhi K, Doho G, Moreno CS, Vertino PM, Bernal-Mizarchi L, Lonial S, Boise LH, Rossi M, Kowalski J, Qin ZS

Cancer informatics.. 2014 13 (Suppl 2):49-53. Epub 09/21/2014.

Zhou W, Marcus AI, Vertino PM

Chinese journal of cancer.. 2013 August 32 (8):427-33. Epub 05/14/2013.

Yang Z, Garcia A, Xu S, Powell DR, Vertino PM, Singh S, Marcus AI

PloS one.. 2013 8 (9):e75069. Epub 09/12/2013.

Duncan CG, Barwick BG, Jin G, Rago C, Kapoor-Vazirani P, Powell DR, Chi JT, Bigner DD, Vertino PM, Yan H

Genome research.. 2012 December 22 (12):2339-55. Epub 08/16/2012.

Hashimoto H, Liu Y, Upadhyay AK, Chang Y, Howerton SB, Vertino PM, Zhang X, Cheng X

Nucleic acids research.. 2012 June 40 (11):4841-9. Epub 02/22/2012.

Vertino PM, Wade PA

Molecular cell.. 2012 March 3045 (6):708-9. Epub 1900 01 01.

Thaiparambil JT, Bender L, Ganesh T, Kline E, Patel P, Liu Y, Tighiouart M, Vertino PM, Harvey RD, Garcia A, Marcus AI

International journal of cancer.. 2011 December 1129 (11):2744-55. Epub 05/02/2011.

Zhu D, Hunter SB, Vertino PM, Van Meir EG

Cancer research.. 2011 September 171 (17):5859-70. Epub 07/01/2011.

Kapoor-Vazirani P, Kagey JD, Vertino PM

Molecular and cellular biology.. 2011 April 31 (8):1594-609. Epub 02/14/2011.

Hashimoto H, Vertino PM, Cheng X

Epigenomics.. 2010 October 2 (5):657-69. Epub 1900 01 01.

Kagey JD, Kapoor-Vazirani P, McCabe MT, Powell DR, Vertino PM

Molecular cancer research : MCR.. 2010 July 8 (7):1048-59. Epub 06/29/2010.

Iskow RC, McCabe MT, Mills RE, Torene S, Pittard WS, Neuwald AF, Van Meir EG, Vertino PM, Devine SE

Cell.. 2010 June 25141 (7):1253-61. Epub 1900 01 01.

Lund MJ, Butler EN, Hair BY, Ward KC, Andrews JH, Oprea-Ilies G, Bayakly AR, O'Regan RM, Vertino PM, Eley JW

Cancer.. 2010 June 1116 (11):2549-59. Epub 1900 01 01.

McCabe MT, Powell DR, Zhou W, Vertino PM

Cancer genetics and cytogenetics.. 2010 March 197 (2):130-41. Epub 1900 01 01.

McCabe MT, Brandes JC, Vertino PM

Clinical cancer research : an official journal of the American Association for Cancer Research.. 2009 June 1515 (12):3927-37. Epub 06/09/2009.

Lucas ME, Crider KS, Powell DR, Kapoor-Vazirani P, Vertino PM

The Journal of biological chemistry.. 2009 May 29284 (22):14698-709. Epub 03/25/2009.

Parsons MJ, Patel P, Brat DJ, Colbert L, Vertino PM

Cancer research.. 2009 March 169 (5):1706-11. Epub 02/17/2009.

McCabe MT, Lee EK, Vertino PM

Cancer research.. 2009 January 169 (1):282-91. Epub 1900 01 01.

Zhong D, Liu X, Khuri FR, Sun SY, Vertino PM, Zhou W

Cancer research.. 2008 September 1568 (18):7270-7. Epub 1900 01 01.

Guo L, Zhong D, Lau S, Liu X, Dong XY, Sun X, Yang VW, Vertino PM, Moreno CS, Varma V, Dong JT, Zhou W

Molecular cancer research : MCR.. 2008 September 6 (9):1421-30. Epub 1900 01 01.

Kapoor-Vazirani P, Kagey JD, Powell DR, Vertino PM

Cancer research.. 2008 August 1568 (16):6810-21. Epub 1900 01 01.

Subramanian K, Jia D, Kapoor-Vazirani P, Powell DR, Collins RE, Sharma D, Peng J, Cheng X, Vertino PM

Molecular cell.. 2008 May 930 (3):336-47. Epub 1900 01 01.

Zhang S, Schafer-Hales K, Khuri FR, Zhou W, Vertino PM, Marcus AI

Cancer research.. 2008 February 168 (3):740-8. Epub 1900 01 01.

Evans CO, Moreno CS, Zhan X, McCabe MT, Vertino PM, Desiderio DM, Oyesiku NM

Pituitary.. 2008 11 (3):231-45. Epub 1900 01 01.

Saxena NK, Vertino PM, Anania FA, Sharma D

The Journal of biological chemistry.. 2007 May 4282 (18):13316-25. Epub 03/07/2007.

Sun X, Zhou Y, Otto KB, Wang M, Chen C, Zhou W, Subramanian K, Vertino PM, Dong JT

Journal of cancer research and clinical oncology.. 2007 February 133 (2):103-5. Epub 08/24/2006.

Parsons MJ, Vertino PM

Oncogene.. 2006 November 225 (52):6948-58. Epub 05/22/2006.

Zhong D, Guo L, de Aguirre I, Liu X, Lamb N, Sun SY, Gal AA, Vertino PM, Zhou W

Lung cancer : journal of the International Association for the Study of Lung Cancer.. 2006 September 53 (3):285-94. Epub 07/05/2006.

Sharma D, Saxena NK, Davidson NE, Vertino PM

Cancer research.. 2006 June 1566 (12):6370-8. Epub 1900 01 01.

Sharma D, Saxena NK, Vertino PM, Anania FA

Endocrine-related cancer.. 2006 June 13 (2):629-40. Epub 1900 01 01.

Feltus FA, Lee EK, Costello JF, Plass C, Vertino PM

Genomics.. 2006 May 87 (5):572-9. Epub 02/17/2006.

Stone AR, Bobo W, Brat DJ, Devi NS, Van Meir EG, Vertino PM

The American journal of pathology.. 2004 October 165 (4):1151-61. Epub 1900 01 01.

Sharma D, Vertino PM

Cancer biology & therapy.. 2004 June 3 (6):549-50. Epub 06/24/2004.

McConnell BB, Vertino PM

Apoptosis : an international journal on programmed cell death.. 2004 January 9 (1):5-18. Epub 1900 01 01.

Feltus FA, Lee EK, Costello JF, Plass C, Vertino PM

Proceedings of the National Academy of Sciences of the United States of America.. 2003 October 14100 (21):12253-8. Epub 09/30/2003.

Levine JJ, Stimson-Crider KM, Vertino PM

Oncogene.. 2003 May 2922 (22):3475-88. Epub 1900 01 01.

Costello JF, Vertino PM

Nature genetics.. 2002 June 31 (2):123-4. Epub 1900 01 01.

Stimson KM, Vertino PM

The Journal of biological chemistry.. 2002 February 15277 (7):4951-8. Epub 12/03/2001.

Vertino PM, Sekowski JA, Coll JM, Applegren N, Han S, Hickey RJ, Malkas LH

Cell cycle.. 2002 1 (6):416-23. Epub 1900 01 01.

Marfatia KA, Harreman MT, Fanara P, Vertino PM, Corbett AH

Gene.. 2001 March 21266 (1-2):45-56. Epub 1900 01 01.

Conway KE, McConnell BB, Bowring CE, Donald CD, Warren ST, Vertino PM

Cancer research.. 2000 November 1560 (22):6236-42. Epub 1900 01 01.

McConnell BB, Vertino PM

Cancer research.. 2000 November 1560 (22):6243-7. Epub 1900 01 01.

Baylin SB, Herman JG, Graff JR, Vertino PM, Issa JP

Advances in cancer research.. 1998 72 :141-96. Epub 1900 01 01.

Ferguson AT, Vertino PM, Spitzner JR, Baylin SB, Muller MT, Davidson NE

The Journal of biological chemistry.. 1997 December 19272 (51):32260-6. Epub 1900 01 01.

Graff JR, Herman JG, Myöhänen S, Baylin SB, Vertino PM

The Journal of biological chemistry.. 1997 August 29272 (35):22322-9. Epub 1900 01 01.

Yoder JA, Yen RW, Vertino PM, Bestor TH, Baylin SB

The Journal of biological chemistry.. 1996 December 6271 (49):31092-7. Epub 1900 01 01.

Issa JP, Vertino PM, Boehm CD, Newsham IF, Baylin SB

Proceedings of the National Academy of Sciences of the United States of America.. 1996 October 1593 (21):11757-62. Epub 1900 01 01.

Vertino PM, Yen RW, Gao J, Baylin SB

Molecular and cellular biology.. 1996 August 16 (8):4555-65. Epub 1900 01 01.

Vertino PM, Issa JP, Pereira-Smith OM, Baylin SB

Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.. 1994 December 5 (12):1395-402. Epub 1900 01 01.

Issa JP, Vertino PM, Wu J, Sazawal S, Celano P, Nelkin BD, Hamilton SR, Baylin SB

Journal of the National Cancer Institute.. 1993 August 485 (15):1235-40. Epub 1900 01 01.

Celano P, Vertino PM, Casero RA

BioTechniques.. 1993 July 15 (1):26-8. Epub 1900 01 01.

Vertino PM, Spillare EA, Harris CC, Baylin SB

Cancer research.. 1993 April 153 (7):1684-9. Epub 1900 01 01.

Yen RW, Vertino PM, Nelkin BD, Yu JJ, el-Deiry W, Cumaraswamy A, Lennon GG, Trask BJ, Celano P, Baylin SB

Nucleic acids research.. 1992 May 1120 (9):2287-91. Epub 1900 01 01.

Vertino PM, Beerman TA, Kelly EJ, Bergeron RJ, Porter CW

Molecular pharmacology.. 1991 April 39 (4):487-94. Epub 1900 01 01.

Vertino PM, Bergeron RJ, Cavanaugh PF, Porter CW

Biopolymers.. 1987 May 26 (5):691-703. Epub 1900 01 01.