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Thu H. Le, M.D.

Thu H. Le, M.D.

Nephrology

5 out of 5 stars
UR Medicine Faculty The University of Rochester Medical Faculty Group (URMFG) consists of over 900 specialist and primary care providers spanning 19 departments. URMFG is certified by the National Committee for Quality Assurance.
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Contact

Locations

General and Transplant Nephrology - Rochester

601 Elmwood Avenue, 2nd & 3rd Floors
Rochester, NY 14642

About Me

Dr. Le is Professor of Medicine, and Chief of the Division of Nephrology. Her clinical practice focuses on the care of patients with hypertension and chronic kidney disease. She applies her knowledge and extensive research experience in renal physiology to her clinical practice. She has an active...
Dr. Le is Professor of Medicine, and Chief of the Division of Nephrology. Her clinical practice focuses on the care of patients with hypertension and chronic kidney disease. She applies her knowledge and extensive research experience in renal physiology to her clinical practice. She has an active research program in mechanisms of hypertension and genetics of chronic kidney disease using mouse models, and is also conducting an NIH funded clinical trial in chronic kidney disease.

Certified Specialties

Nephrology - American Board of Internal Medicine

Faculty Appointments

Professor - Department of Medicine, Nephrology (SMD)

John J. Kuiper Distinguished Professorship - Department of Medicine, Nephrology (SMD)

Chief - Department of Medicine, Nephrology (SMD)

Credentials

Residency & Fellowship

Fellowship, Nephrology, Duke University. 1996 - 2000

Residency, Internal Medicine, Duke University. 1993 - 1996

Education

MD | George Washington University School of Medicine & Health Sciences. 1993

Research

Scientific Approach: My laboratory studies renal mechanisms of hypertension and genetic determinants of susceptibility to kidney disease progression. We use the mouse as a model system, and translate our findings in human cohorts.

Role of GSTM1 deficiency in chronic kidney disease progress...
Scientific Approach: My laboratory studies renal mechanisms of hypertension and genetic determinants of susceptibility to kidney disease progression. We use the mouse as a model system, and translate our findings in human cohorts.

Role of GSTM1 deficiency in chronic kidney disease progression: Using classical genetic studies, my lab identified that Gstm1 is a candidate gene for renal vascular remodeling in a mouse model. Through translational studies, we reported that the null allele of GSTM1 gene is associated with accelerated kidney disease progression in the African American Study of Hypertension and Kidney Disease (AASK) Trial participants; and this was replicated in the Atherosclerosis Risk in Communities (ARIC) cohort in both European and African Americans. To establish causality, we showed that deletion of Gstm1 gene in the mouse increases renal oxidative stress and inflammation. Moreover, Gstm1 knockout mice, and not their wild-type littermates, derive a renal protective effect when their diet was supplemented with sulforaphane-rich broccoli powder. Importantly, we also showed in ARIC that while patients with the GSTM1 null allele are more at risk for kidney disease progression and kidney failure, these patients also derive more benefit from high intake of cruciferous vegetables compared to those carrying one or two active GSTM1 alleles. Our work has advanced the conceptual understanding of gene-environment interaction in kidney disease and precision medicine. These findings received world-wide press release in 2020. Our work has evolved to an NIH funded clinical trial NCT05797506 to test the safety and efficacy of sulforaphane supplement in CKD stages 3-4. We are currently pursuing the GSTM1-Transsulfuration Metabolic Axis as a mechanistic pathway that can be targeted therapeutically in precision medicine.

Collectrin (Tmem27) in hypertension and salt-sensitivity: The goal of this project is to define the physiological role of collectrin, Tmem27, a chaperone of amino acid transporters, in blood pressure homeostasis. Using global collectrin knockout mouse line, we previously reported that collectrin, by regulating arginine uptake, modulates nitric oxide and superoxide balance, and therefore blood pressure and salt-sensitivity. Using a tissue-specific knockout approach to delineate the tissue-collectrin-nitric oxide synthase axis and renal mechanisms (tubular epithelial regulation versus renal blood flow) by which collectrin influences blood pressure and the adaptive response to high salt intake, we identified that loss of collectrin in the proximal tubule is sufficient to cause hypertension, but not salt sensitivity. Our data supports the notion that vascular dysfunction, particularly alteration in renal blood flow, is required for salt sensitivity. In addition, using a translational approach, we observed sex-specific single-nucleotide polymorphism association with diastolic blood pressure in a large Latino cohort, implicating a role of collectrin in human hypertension.

Collectrin (Tmem27) in kidney cancer: More recently, we identified that absence of collectrin expression in kidney tumor is associated with more aggressive tumor characteristics and poorer all-cause mortality and disease-free survival in patients with clear cell renal cell carcinoma (cc RCC). Efforts are underway to define molecular mechanism by which collectrin impacts clinical outcomes in cc RCC.

Publications: For a full list of publications, please see the following link:
http://www.ncbi.nlm.nih.gov/sites/myncbi/thu.le.1/bibliography/40454872/public/?sort=date&direction=ascending

Clinical Trials

Safety, Feasibility and Efficacy of Sulforaphane (Avmacol Extra Strength) in Chronic Kidney Disease - Randomized, Double-blinded, Placebo-controlled Trial

Lead Researcher: Thu Le

This study will determine if taking a daily broccoli supplement (Avmacol ES) can decrease kidney disease progression rate and inflammation in patients with Chronic Kidney Disease (CKD). The study will enroll 100 patients from the Kidney Clinic in AC3...

Publications

Journal Articles

Cabalar I, Le TH, Silber A, O'Hara M, Abdallah B, Parikh M, Busch R

The American journal of the medical sciences.. 2024 April 16 Epub 04/16/2024.

Drury ER, Wu J, Gigliotti JC, Le TH

Physiological reviews.. 2024 January 1104 (1):199-251. Epub 07/21/2023.

Wu J, Le TH

Kidney international.. 2023 October 104 (4):649-651. Epub 1900 01 01.

Erdbrügger U, Hoorn EJ, Le TH, Blijdorp CJ, Burger D

Kidney360.. 2023 February 14 (2):245-257. Epub 12/18/2022.

Chu PL, Gigliotti JC, Cechova S, Bodonyi-Kovacs G, Wang YT, Chen L, Wassertheil-Smoller S, Cai J, Isakson BE, Franceschini N, Le TH

American journal of physiology. Renal physiology.. 2023 January 1324 (1):F30-F42. Epub 10/20/2022.

Choung HYG, Moore C, Le TH, Guirguis P, McKeown JM, Jean-Gilles J, Goldman B

Nephron.. 2023 147 (7):424-433. Epub 02/06/2023.

Levy R, Le TH

Kidney360.. 2022 December 293 (12):2153-2163. Epub 10/18/2022.

Ahmed M, Love T, Moore C, Le TH, Jean-Gilles J, Goldman B, Choung HYG

Renal failure.. 2022 December 44 (1):581-593. Epub 1900 01 01.

Grewal R, Choung HYG, Roberts LL, Beane T, Chen L, Gilroy DX, Rappold PM, Le TH

Acta oncologica.. 2022 December 61 (12):1507-1511. Epub 11/11/2022.

Levy RV, Reidy KJ, Le TH, David V, Winkler C, Xu Y, Warady B, Furth S, Kaskel F, Melamed ML

American journal of kidney diseases : the official journal of the National Kidney Foundation.. 2022 July 80 (1):79-86. Epub 12/04/2021.

Franceschini N, Le TH

Journal of the American Society of Nephrology : JASN.. 2022 March 33 (3):461-462. Epub 1900 01 01.

Le TH

Hypertension.. 2021 September 78 (4):936-945. Epub 08/30/2021.

Liebman SE, Le TH

Nutrients.. 2021 January 1813 (1)Epub 01/18/2021.

La Salvia S, Musante L, Lannigan J, Gigliotti JC, Le TH, Erdbrügger U

American journal of physiology. Renal physiology.. 2020 November 1319 (5):F868-F875. Epub 10/05/2020.

Levy DS, Grewal R, Le TH

American journal of physiology. Renal physiology.. 2020 October 1319 (4):F618-F623. Epub 08/24/2020.

Martin DE, Harris DCH, Jha V, Segantini L, Demme RA, Le TH, McCann L, Sands JM, Vong G, Wolpe PR, Fontana M, London GM, Vanderhaegen B, Vanholder R,

Nature reviews. Nephrology.. 2020 October 16 (10):603-613. Epub 06/25/2020.

DeLalio LJ, Masati E, Mendu S, Ruddiman CA, Yang Y, Johnstone SR, Milstein JA, Keller TCS, Weaver RB, Guagliardo NA, Best AK, Ravichandran KS, Bayliss DA, Sequeira-Lopez MLS, Sonkusare SN, Shu XH, Desai B, Barrett PQ, Le TH, Gomez RA, Isakson BE

Kidney international.. 2020 September 98 (3):630-644. Epub 05/21/2020.

Musante L, Bontha SV, La Salvia S, Fernandez-Piñeros A, Lannigan J, Le TH, Mas V, Erdbrügger U

Scientific reports.. 2020 February 2810 (1):3701. Epub 02/28/2020.

Gigliotti JC, Tin A, Pourafshar S, Cechova S, Wang YT, Sung SJ, Bodonyi-Kovacs G, Cross JV, Yang G, Nguyen N, Chan F, Rebholz C, Yu B, Grove ML, Grams ME, Köttgen A, Scharpf R, Ruiz P, Boerwinkle E, Coresh J, Le TH

Journal of the American Society of Nephrology : JASN.. 2020 January 31 (1):102-116. Epub 11/14/2019.

Good ME, Musante L, La Salvia S, Howell NL, Carey RM, Le TH, Isakson BE, Erdbrügger U

Hypertension.. 2020 January 75 (1):218-228. Epub 11/25/2019.

Erdbrügger U, Le TH

American journal of physiology. Renal physiology.. 2019 September 1317 (3):F641-F647. Epub 07/17/2019.

Li J, Cechova S, Wang L, Isakson BE, Le TH, Shi W

American journal of physiology. Renal physiology.. 2019 June 1316 (6):F1141-F1150. Epub 04/03/2019.

Guagliardo NA, Yao J, Stipes EJ, Cechova S, Le TH, Bayliss DA, Breault DT, Barrett PQ

Hypertension.. 2019 February 73 (2):407-414. Epub 1900 01 01.

Morris AP, Le TH, Wu H, Akbarov A, van der Most PJ, Hemani G, Smith GD, Mahajan A, Gaulton KJ, Nadkarni GN, Valladares-Salgado A, Wacher-Rodarte N, Mychaleckyj JC, Dueker ND, Guo X, Hai Y, Haessler J, Kamatani Y, Stilp AM, Zhu G, Cook JP, Ärnlöv J, Blanton SH, de Borst MH, Bottinger EP, Buchanan TA, Cechova S, Charchar FJ, Chu PL, Damman J, Eales J, Gharavi AG, Giedraitis V, Heath AC, Ipp E, Kiryluk K, Kramer HJ, Kubo M, Larsson A, Lindgren CM, Lu Y, Madden PAF, Montgomery GW, Papanicolaou GJ, Raffel LJ, Sacco RL, Sanchez E, Stark H, Sundstrom J, Taylor KD, Xiang AH, Zivkovic A, Lind L, Ingelsson E, Martin NG, Whitfield JB, Cai J, Laurie CC, Okada Y, Matsuda K, Kooperberg C, Chen YI, Rundek T, Rich SS, Loos RJF, Parra EJ, Cruz M, Rotter JI, Snieder H, Tomaszewski M, Humphreys BD, Franceschini N

Nature communications.. 2019 January 310 (1):29. Epub 01/03/2019.

Artamonov MV, Sonkusare SK, Good ME, Momotani K, Eto M, Isakson BE, Le TH, Cope EL, Derewenda ZS, Derewenda U, Somlyo AV

Science signaling.. 2018 October 3011 (554)Epub 10/30/2018.

Brown IAM, Diederich L, Good ME, DeLalio LJ, Murphy SA, Cortese-Krott MM, Hall JL, Le TH, Isakson BE

Arteriosclerosis, thrombosis, and vascular biology.. 2018 September 38 (9):1969-1985. Epub 1900 01 01.

Cechova S, Dong F, Chan F, Kelley MJ, Ruiz P, Le TH

Journal of the American Society of Nephrology : JASN.. 2018 January 29 (1):155-167. Epub 10/09/2017.

Tin A, Scharpf R, Estrella MM, Yu B, Grove ML, Chang PP, Matsushita K, Köttgen A, Arking DE, Boerwinkle E, Le TH, Coresh J, Grams ME

Journal of the American Society of Nephrology : JASN.. 2017 November 28 (11):3345-3352. Epub 07/18/2017.

Gigliotti JC, Le TH

Journal of the American Society of Nephrology : JASN.. 2017 November 28 (11):3131-3133. Epub 10/16/2017.

Sofer T, Wong Q, Hartwig FP, Taylor K, Warren HR, Evangelou E, Cabrera CP, Levy D, Kramer H, Lange LA, Horta BL, , Kerr KF, Reiner AP, Franceschini N

Scientific reports.. 2017 September 47 (1):10348. Epub 09/04/2017.

Niu F, Zhou J, Le TH, Ma JZ

Statistical methods in medical research.. 2017 June 26 (3):1519-1531. Epub 05/13/2015.

Chu PL, Gigliotti JC, Cechova S, Bodonyi-Kovacs G, Chan F, Ralph DL, Howell N, Kalantari K, Klibanov AL, Carey RM, McDonough AA, Le TH

Journal of the American Society of Nephrology : JASN.. 2017 June 28 (6):1826-1837. Epub 01/06/2017.

Liang J, Le TH, Edwards DRV, Tayo BO, Gaulton KJ, Smith JA, Lu Y, Jensen RA, Chen G, Yanek LR, Schwander K, Tajuddin SM, Sofer T, Kim W, Kayima J, McKenzie CA, Fox E, Nalls MA, Young JH, Sun YV, Lane JM, Cechova S, Zhou J, Tang H, Fornage M, Musani SK, Wang H, Lee J, Adeyemo A, Dreisbach AW, Forrester T, Chu PL, Cappola A, Evans MK, Morrison AC, Martin LW, Wiggins KL, Hui Q, Zhao W, Jackson RD, Ware EB, Faul JD, Reiner AP, Bray M, Denny JC, Mosley TH, Palmas W, Guo X, Papanicolaou GJ, Penman AD, Polak JF, Rice K, Taylor KD, Boerwinkle E, Bottinger EP, Liu K, Risch N, Hunt SC, Kooperberg C, Zonderman AB, Laurie CC, Becker DM, Cai J, Loos RJF, Psaty BM, Weir DR, Kardia SLR, Arnett DK, Won S, Edwards TL, Redline S, Cooper RS, Rao DC, Rotter JI, Rotimi C, Levy D, Chakravarti A, Zhu X, Franceschini N

PLoS genetics.. 2017 May 13 (5):e1006728. Epub 05/12/2017.

Yang G, Chu PL, Rump LC, Le TH, Stegbauer J

Antioxidants & redox signaling.. 2017 April 2026 (12):645-659. Epub 01/12/2017.

Sung SJ, Ge Y, Dai C, Wang H, Fu SM, Sharma R, Hahn YS, Yu J, Le TH, Okusa MD, Bolton WK, Lawler JR

The Journal of immunology : official journal of the American Association of Immunologists.. 2017 April 1198 (7):2589-2601. Epub 02/20/2017.

Dolina JS, Cechova S, Rudy CK, Sung SJ, Tang WW, Lee J, Hahn YS, Le TH

The Journal of immunology : official journal of the American Association of Immunologists.. 2017 March 15198 (6):2341-2351. Epub 02/03/2017.

Sung SJ, Li L, Huang L, Lawler J, Ye H, Rosin DL, Vincent IS, Le TH, Yu J, Görldt N, Schrader J, Okusa MD

Journal of the American Society of Nephrology : JASN.. 2017 March 28 (3):888-902. Epub 09/14/2016.

He KY, Wang H, Cade BE, Nandakumar P, Giri A, Ware EB, Haessler J, Liang J, Smith JA, Franceschini N, Le TH, Kooperberg C, Edwards TL, Kardia SL, Lin X, Chakravarti A, Redline S, Zhu X

PLoS genetics.. 2017 March 13 (3):e1006678. Epub 03/27/2017.

Keller TC, Butcher JT, Broseghini-Filho GB, Marziano C, DeLalio LJ, Rogers S, Ning B, Martin JN, Chechova S, Cabot M, Shu X, Best AK, Good ME, Simão Padilha A, Purdy M, Yeager M, Peirce SM, Hu S, Doctor A, Barrett E, Le TH, Columbus L, Isakson BE

Hypertension.. 2016 December 68 (6):1494-1503. Epub 10/31/2016.

Bodonyi-Kovacs G, Ma JZ, Chang J, Lipkowitz MS, Kopp JB, Winkler CA, Le TH

Journal of the American Society of Nephrology : JASN.. 2016 October 27 (10):3140-3152. Epub 03/03/2016.

Mahajan A, Rodan AR, Le TH, Gaulton KJ, Haessler J, Stilp AM, Kamatani Y, Zhu G, Sofer T, Puri S, Schellinger JN, Chu PL, Cechova S, van Zuydam N, , , Arnlov J, Flessner MF, Giedraitis V, Heath AC, Kubo M, Larsson A, Lindgren CM, Madden PAF, Montgomery GW, Papanicolaou GJ, Reiner AP, Sundström J, Thornton TA, Lind L, Ingelsson E, Cai J, Martin NG, Kooperberg C, Matsuda K, Whitfield JB, Okada Y, Laurie CC, Morris AP, Franceschini N

American journal of human genetics.. 2016 September 199 (3):636-646. Epub 1900 01 01.

Erdbrügger U, Le TH

Journal of the American Society of Nephrology : JASN.. 2016 January 27 (1):12-26. Epub 08/06/2015.

Mas VR, Le TH, Maluf DG

Transplantation.. 2016 January 100 (1):23-38. Epub 1900 01 01.

Billaud M, Chiu YH, Lohman AW, Parpaite T, Butcher JT, Mutchler SM, DeLalio LJ, Artamonov MV, Sandilos JK, Best AK, Somlyo AV, Thompson RJ, Le TH, Ravichandran KS, Bayliss DA, Isakson BE

Science signaling.. 2015 February 178 (364):ra17. Epub 02/17/2015.

Straub AC, Butcher JT, Billaud M, Mutchler SM, Artamonov MV, Nguyen AT, Johnson T, Best AK, Miller MP, Palmer LA, Columbus L, Somlyo AV, Le TH, Isakson BE

Arteriosclerosis, thrombosis, and vascular biology.. 2014 December 34 (12):2594-600. Epub 10/02/2014.

Chu PL, Le TH

Current hypertension reports.. 2014 November 16 (11):490. Epub 1900 01 01.

Franceschini N, Le TH

American journal of physiology. Renal physiology.. 2014 January 1306 (1):F1-F11. Epub 10/16/2013.

Cechova S, Zeng Q, Billaud M, Mutchler S, Rudy CK, Straub AC, Chi L, Chan FR, Hu J, Griffiths R, Howell NL, Madsen K, Jensen BL, Palmer LA, Carey RM, Sung SS, Malakauskas SM, Isakson BE, Le TH

Circulation.. 2013 October 15128 (16):1770-80. Epub 09/18/2013.

Chang J, Ma JZ, Zeng Q, Cechova S, Gantz A, Nievergelt C, O'Connor D, Lipkowitz M, Le TH

American journal of physiology. Renal physiology.. 2013 February 15304 (4):F348-55. Epub 12/05/2012.

Lai EY, Luo Z, Onozato ML, Rudolph EH, Solis G, Jose PA, Wellstein A, Aslam S, Quinn MT, Griendling K, Le T, Li P, Palm F, Welch WJ, Wilcox CS

American journal of physiology. Renal physiology.. 2012 July 1303 (1):F64-74. Epub 04/04/2012.

Verlander JW, Hong S, Pech V, Bailey JL, Agazatian D, Matthews SW, Coffman TM, Le T, Inagami T, Whitehill FM, Weiner ID, Farley DB, Kim YH, Wall SM

American journal of physiology. Renal physiology.. 2011 December 301 (6):F1314-25. Epub 09/14/2011.

Gurley SB, Riquier-Brison ADM, Schnermann J, Sparks MA, Allen AM, Haase VH, Snouwaert JN, Le TH, McDonough AA, Koller BH, Coffman TM

Cell metabolism.. 2011 April 613 (4):469-475. Epub 1900 01 01.

Sparks MA, Parsons KK, Stegbauer J, Gurley SB, Vivekanandan-Giri A, Fortner CN, Snouwaert J, Raasch EW, Griffiths RC, Haystead TA, Le TH, Pennathur S, Koller B, Coffman TM

Hypertension.. 2011 March 57 (3):577-85. Epub 01/17/2011.

van Esch JH, Gembardt F, Sterner-Kock A, Heringer-Walther S, Le TH, Lassner D, Stijnen T, Coffman TM, Schultheiss HP, Danser AH, Walther T

Cardiovascular research.. 2010 June 186 (3):401-9. Epub 01/12/2010.

Yang Y, Parsons KK, Chi L, Malakauskas SM, Le TH

Hypertension.. 2009 December 54 (6):1360-8. Epub 10/12/2009.

Branagan NM, Higgins SP, Halim SA, Le TH

Clinical and experimental dermatology.. 2009 July 34 (5):e127-9. Epub 04/27/2009.

Malakauskas SM, Kourany WM, Zhang XY, Lu D, Stevens RD, Koves TR, Hohmeier HE, Muoio DM, Newgard CB, Le TH

Molecular endocrinology.. 2009 June 23 (6):881-92. Epub 02/26/2009.

Yasuhara A, Wada J, Malakauskas SM, Zhang Y, Eguchi J, Nakatsuka A, Murakami K, Kanzaki M, Teshigawara S, Yamagata K, Le TH, Makino H

Circulation.. 2008 November 18118 (21):2146-55. Epub 11/03/2008.

Gembardt F, Heringer-Walther S, van Esch JH, Sterner-Kock A, van Veghel R, Le TH, Garrelds IM, Coffman TM, Danser AH, Schultheiss HP, Walther T

FASEB journal : official publication of the Federation of American Societies for Experimental Biology.. 2008 August 22 (8):3068-77. Epub 05/22/2008.

Le TH, Coffman TM

Current opinion in nephrology and hypertension.. 2008 January 17 (1):57-63. Epub 1900 01 01.

Salzler HR, Griffiths R, Ruiz P, Chi L, Frey C, Marchuk DA, Rockman HA, Le TH

Kidney international.. 2007 November 72 (10):1226-32. Epub 09/12/2007.

Malakauskas SM, Quan H, Fields TA, McCall SJ, Yu MJ, Kourany WM, Frey CW, Le TH

American journal of physiology. Renal physiology.. 2007 February 292 (2):F533-44. Epub 09/19/2006.

Crowley SD, Gurley SB, Herrera MJ, Ruiz P, Griffiths R, Kumar AP, Kim HS, Smithies O, Le TH, Coffman TM

Proceedings of the National Academy of Sciences of the United States of America.. 2006 November 21103 (47):17985-90. Epub 11/07/2006.

Gurley SB, Allred A, Le TH, Griffiths R, Mao L, Philip N, Haystead TA, Donoghue M, Breitbart RE, Acton SL, Rockman HA, Coffman TM

The Journal of clinical investigation.. 2006 August 116 (8):2218-25. Epub 07/27/2006.

Le TH, Coffman TM

The Journal of clinical investigation.. 2006 April 116 (4):866-9. Epub 1900 01 01.

Ouyang X, Le TH, Roncal C, Gersch C, Herrera-Acosta J, Rodriguez-Iturbe B, Coffman TM, Johnson RJ, Mu W

American journal of physiology. Renal physiology.. 2005 October 289 (4):F902-10. Epub 05/31/2005.

Crowley SD, Gurley SB, Oliverio MI, Pazmino AK, Griffiths R, Flannery PJ, Spurney RF, Kim HS, Smithies O, Le TH, Coffman TM

The Journal of clinical investigation.. 2005 April 115 (4):1092-9. Epub 1900 01 01.

Le TH, Oliverio MI, Kim HS, Salzler H, Dash RC, Howell DN, Smithies O, Bronson S, Coffman TM

Physiological genomics.. 2004 August 1118 (3):290-8. Epub 08/11/2004.

Le TH, Fogo AB, Salzler HR, Vinogradova T, Oliverio MI, Marchuk DA, Coffman TM

Hypertension.. 2004 February 43 (2):445-51. Epub 01/12/2004.

Le TH, Kim HS, Allen AM, Spurney RF, Smithies O, Coffman TM

Hypertension.. 2003 October 42 (4):507-14. Epub 09/08/2003.

Le TH, Coffman TM

The Journal of clinical investigation.. 2003 February 111 (4):441-3. Epub 1900 01 01.

Gurley SB, Le TH, Coffman TM

Cold Spring Harbor symposia on quantitative biology.. 2002 67 :451-7. Epub 1900 01 01.

Audoly LP, Le TH, Coffman TM

Current hypertension reports.. 2000 April 2 (2):192-7. Epub 1900 01 01.

Le TH, Coffman TM

Current opinion in nephrology and hypertension.. 1999 July 8 (4):397-403. Epub 1900 01 01.

Oliverio MI, Kim HS, Ito M, Le T, Audoly L, Best CF, Hiller S, Kluckman K, Maeda N, Smithies O, Coffman TM

Proceedings of the National Academy of Sciences of the United States of America.. 1998 December 2295 (26):15496-501. Epub 1900 01 01.

Sharara AI, Le TH, Suhocki P, Jowell PS

Gastrointestinal endoscopy.. 1995 August 42 (2):176-7. Epub 1900 01 01.

Ratings & Comments

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Ratings

During this visit, did this provider spend enough time with you?

5.0 stars

During this visit, did this provider show respect for what you had to say?

5.0 stars

During this visit did this provider give you easy to understand information about these health questions or concerns?

4.9 stars

During this visit, did this provider listen carefully to you?

5.0 stars

During this visit, did this provider explain things in a way that was easy to understand?

5.0 stars

Patient Comments

Dr. Le was everything I would want in a doctor.

Jul 28, 2024

5.0 stars

Very friendly and very concerned about my health condition very good

Feb 03, 2024

Dr. Le is awesome! Very caring and compensate! Take time to listen and explain things.

Nov 24, 2023

5.0 stars

I was very impressed with Dr. Le - the time she spent with me, her caring demeanor - everything.

Sep 09, 2023

5.0 stars

Dr. Le is terrific!

May 05, 2023

5.0 stars

Best dr. I have ever had.

Apr 05, 2023

5.0 stars

I was a little nervous about what she told me but she calmed me down made it alright.

Apr 04, 2023

I feel that Dr Le has my very best interests as her top priority

Mar 05, 2023

3.8 stars

Not much discussion r/t my chronic condition; mostly review of bloodwork findings.

Dec 29, 2022

5.0 stars

Dr. Le was great - Knowledgeable, and caring with the ability to project confidence in her desire to maintain my health.

Aug 30, 2022

5.0

Dr. Le always treats me with respect and humanity. I'm most trusting and comfortable with her.

Jul 19, 2022

5.0

Showed good medical judgment.

May 03, 2022