Md Nasir Uddin, Ph.D.
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Md Nasir Uddin, Ph.D.
About Me
Faculty Appointments
Assistant Professor - Department of Neurology, General Neurology (SMD)
Assistant Professor - Department of Biomedical Engineering (SMD) - Joint
Credentials
Education
PhD | University of Alberta. Biomedical Engineering. 2015
Awards
NIH Director's Pioneer Award (DP1). 2024
Office of AIDS Research (OAR) Innovation Award. 2023
Magna Cum Laude. 2014
Student Scholarship. 2010
SGS Merit Award. 2008
Research
His research revolves around the development and appli...
His research revolves around the development and application of advanced MRI techniques to gain profound insights into the structure and function of the human brain, encompassing both healthy and diseased states. Notably, his expertise extends to the investigation of various neurological conditions, including Multiple Sclerosis, HIV, Cerebral Small Vessel Disease, Stroke, Parkinson's Disease, and Hypertension.
His research interests span across several key areas, including:
1. Development of novel MRI methods and image processing pipelines to study neuroinflammation and neuronal injury.
2. Investigation of neuroinflammation and neurodegeneration through diffusion MRI methods, such as free water imaging (FWI), neurite orientation dispersion and density imaging (NODDI), b-tensor encoding; T2-based myelin water imaging (MWI), and multifrequency MR Elastography.
3.. Exploration of iron-sensitive measures using quantitative susceptibility mapping (QSM) and relaxometry mappings (T2, T2*, T2鈥) to identify potential biomarkers.
4. Examination of vascular dysfunction using perfusion MRI and resting-state fMRI-based cerebrovascular reactivity. In addition, he is delving into vascular remodeling using time-of-flight MR Angiography, with the exciting aim of developing an automated AI-based approach for the segmentation and classification of brain arteries, as well as extracting essential vascular features with minimum training datasets.
5. Analysis of the intricate relationship between structural and functional MRI measures, blood markers, and cognitive performance, encompassing both healthy, aging, and clinical populations.
Key Words: MRI, Brain, Neuroimaging, Iron, Myelin, Neuroinflammation, diffusion MRI, Free Water, Multiple Sclerosis, HIV, CSVD, Machine Learning, Deep Learning, Artificial Intelligence.
Publications
Journal Articles
Parker KJ, Kabir IE, Doyley MM, Faiyaz A, Uddin MN, Flores G, Schifitto G
Physics in medicine and biology.. 2024 May 2969 (11)Epub 05/29/2024.
Kornelsen J, McIver T, Uddin MN, Figley CR, Marrie RA, Patel R, Fisk JD, Carter S, Graff L, Mazerolle EL, Bernstein CN,
Brain research bulletin.. 2023 October 15203 :110771. Epub 10/04/2023.
Patel R, Marrie RA, Bernstein CN, Bolton JM, Graff LA, Marriott JJ, Figley CR, Kornelsen J, Mazerolle EL, Helmick C, Uddin MN, Fisk JD
Inflammatory bowel diseases.. 2023 September 22 Epub 09/22/2023.
Murray KD, Tivarus ME, Schifitto G, Uddin MN, Zhong J
Magnetic resonance imaging.. 2023 May 98 :115-123. Epub 01/20/2023.
Patel R, Marrie RA, Bernstein CN, Bolton JM, Graff LA, Marriott JJ, Figley CR, Kornelsen J, Mazerolle EL, Uddin MN, Fisk JD,
Scientific reports.. 2023 March 1513 (1):4317. Epub 03/15/2023.
Singh, MV; Uddin, MN; Covacevich, VM; Sutton, KR; Boodoo, ZD; Peterson, A; Tyrell, A; Brenner, R; Tivarus, ME; Wang, HZ; Sahin, B; Zhong, J; Weber, M; Wang, L; Qiu, X; Maggiwar, SB; Schifitto G.
medRxiv. 2023; : 2023-03.
Faiyaz, A; Doyley, M; Schifitto, G; Uddin, MN.
Frontiers in Neurology. 2023; 14(700): 1-9.
Figley, CR; Figley, TD; Wong, K; Uddin, MN; da Silva, RDC; and Kornelsen, J.
Front. Hum. Neurosci. 2023; 17: 1-8.
Singh M, Uddin MN, Singh VB, Peterson AN, Murray KD, Zhuang Y, Tyrell A, Wang L, Tivarus ME, Zhong J, Qiu X, Schifitto G.
Frontiers in Neurology. 2023; 14: 1240300.
Carter SL, Patel R, Fisk JD, Figley CR, Marrie RA, Mazerolle EL, Uddin MN, Wong K, Graff LA, Bolton JM and Marriott JJ.
Frontiers in Neurology. 2023; 14: 1250894.
Uddin, MN; Tivarus, ME; Schifitto, G; & Rudko, DA.
Frontiers in Neurology. 2023; 14(1328511).
Aja-Fern谩ndez S, Mart铆n-Mart铆n C, Planchuelo-G贸mez 脕, Faiyaz A, Uddin MN, Schifitto G, Tiwari A, Shigwan SJ, Kumar Singh R, Zheng T, Cao Z, Wu D, Blumberg SB, Sen S, Goodwin-Allcock T, Slator PJ, Yigit Avci M, Li Z, Bilgic B, Tian Q, Wang X, Tang Z, Cabezas M, Rauland A, Merhof D, Manzano Maria R, Campos VP, Santini T, da Costa Vieira MA, HashemizadehKolowri S, DiBella E, Peng C, Shen Z, Chen Z, Ullah I, Mani M, Abdolmotalleby H, Eckstrom S, Baete SH, Filipiak P, Dong T, Fan Q, de Luis-Garc铆a R, Trist谩n-Vega A, Pieciak T
NeuroImage. Clinical.. 2023 39 :103483. Epub 07/28/2023.
Weber MT, Finkelstein A, Uddin MN, Reddy EA, Arduino RC, Wang L, Tivarus ME, Zhong J, Qui X, Schifitto G
Neurology.. 2022 June 22 Epub 06/22/2022.
Faiyaz A, Doyley M, Schifitto G, Zhong J, Uddin MN
NMR in biomedicine.. 2022 February 35 (2):e4628. Epub 10/12/2021.
Uddin, MN; Figley, TD; Kornelsen, J; Mazerolle, EL; Helmick, CA; O'Grady, CB; Pirzada, S; Patel, R; Carter, S; Wong, K; Essig, MR; Graff, LA; Bolton, JM; Marriott, JJ; Bernstein, CN; Fisk, JD; Marrie, RA; Figley CR.
Frontiers in Neuroimaging. 2022; 1(970385): 30.
Patel, R; Marrie, RA; Bernstein, CN; Bolton, JM; Graff, LA; Marriott, JJ; Figley, CR; Kornelsen, J; Mazerolle, EL; Uddin, MN; Fisk, JD.
2022; .
Faiyaz, A; Uddin, MN; Schifitto, G.
2022; .
Marrie RA, Patel R, Figley CR, Kornelsen J, Bolton JM, Graff LA, Mazerolle EL, Helmick C, Uddin MN, Figley TD, Marriott JJ, Bernstein CN, Fisk JD
Frontiers in neurology. 2022 13 :910014. Epub 05/24/2022.
Marrie RA, Patel R, Figley CR, Kornelsen J, Bolton JM, Graff LA, Mazerolle EL, Helmick C, O'Grady C, Uddin MN, Marriott JJ, Bernstein CN, Fisk JD,
Multiple sclerosis and related disorders.. 2021 September 54 :103088. Epub 06/17/2021.
Uddin MN, Faiyaz A, Wang L, Zhuang Y, Murray KD, Descoteaux M, Tivarus ME, Weber MT, Zhong J, Qiu X, Schifitto G
Scientific reports.. 2021 April 1511 (1):8273. Epub 04/15/2021.
Uddin MN, Tivarus M, Adams H, Little E, Schifitto G, Lande MB
Hypertension.. 2021 March 377 (3):751-758. Epub 02/10/2021.
Das, S; Yasmin, MR; Arefin, M; Taher, KA; Uddin, MN; Rahman, MA.
Applied Intelligence and Informatics pp 371鈥383. 2021; 1435: 371鈥383.
Murray, KD; Tivarus, MT; Schifitto, G; Uddin, MN; Zhong J.
bioRxiv. 2021; .
Murray KD, Uddin MN, Tivarus ME, Sahin B, Wang HZ, Singh MV, Qiu X, Wang L, Spincemaille P, Wang Y, Maggirwar SB, Zhong J, Schifitto G
NeuroImage. Clinical.. 2021 32 :102786. Epub 08/28/2021.
Finkelstein A, Faiyaz A, Weber MT, Qiu X, Uddin MN, Zhong J, Schifitto G
Frontiers in neurology. 2021 12 :725059. Epub 11/04/2021.
Figley CR, Uddin MN, Wong K, Kornelsen J, Puig J, Figley TD
Frontiers in neuroscience.. 2021 15 :799576. Epub 01/14/2022.
Puig J, Biarnes C, Pedraza S, Vilanova JC, Pamplona R, Fern谩ndez-Real JM, Brugada R, Ramos R, Coll-de-Tuero G, Calvo-Perxas L, Serena J, Rami贸-Torrent脿 L, Gich J, Gallart L, Portero-Otin M, Alberich-Bayarri A, Jimenez-Pastor A, Camacho-Ramos E, Mayneris-Perxachs J, Pineda V, Font R, Prats-Puig A, Gacto ML, Deco G, Escrichs A, Clotet B, Paredes R, Negredo E, Triaire B, Rodr铆guez M, Heredia-Esc谩mez A, Coronado R, de Graaf W, Prevost V, Mitulescu A, Daunis-I-Estadella P, Thi贸-Henestrosa S, Miralles F, Ribas-Ripoll V, Puig-Domingo M, Essig M, Figley CR, Figley TD, Albensi B, Ashraf A, Reiber JHC, Schifitto G, Md Nasir U, Leiva-Salinas C, Wintermark M, Nael K, Vilalta-Franch J, Barretina J, Garre-Olmo J
Mechanisms of ageing and development.. 2020 July 189 :111257. Epub 05/11/2020.
Pirzada S, Uddin MN, Figley TD, Kornelsen J, Puig J, Marrie RA, Mazerolle EL, Fisk JD, Helmick CA, O'Grady CB, Patel R, Figley CR,
Magnetic resonance imaging.. 2020 May 68 :83-94. Epub 01/30/2020.
Uddin, MN; Faiyaz, A; Wang, L; Zhuang, Y; Murray, KD; Descoteaux, M; Tivarus, ME; Weber, MT; Zhong, J; Qiu, X; Schifitto, G.
2020; .
Murray KD, Singh MV, Zhuang Y, Uddin MN, Qiu X, Weber MT, Tivarus ME, Wang HZ, Sahin B, Zhong J, Maggirwar SB, Schifitto G
Frontiers in neurology. 2020 11 :595463. Epub 12/15/2020.
Uddin MN, Figley TD, Solar KG, Shatil AS, Figley CR
Scientific reports.. 2019 February 219 (1):2500. Epub 02/21/2019.
Uddin MN, Figley TD, Figley CR
Magnetic resonance imaging.. 2018 September 51 :35-43. Epub 04/20/2018.
Uddin MN, Figley TD, Marrie RA, Figley CR,
NMR in biomedicine.. 2018 March 31 (3)Epub 01/09/2018.
Shatil AS, Uddin MN, Matsuda KM, Figley CR
Frontiers in medicine.. 2018 5 :31. Epub 02/20/2018.
Uddin MN, McPhee KC, Blevins G, Wilman AH
Magnetic resonance imaging.. 2017 April 37 :21-26. Epub 11/14/2016.
Uddin, MN; Figley, TD; Marrie, RA; Figley CR.
CMBES Proceedings. 2017; 40.
Uddin MN, Lebel RM, Seres P, Blevins G, Wilman AH
Multiple sclerosis : clinical and laboratory research.. 2016 August 22 (9):1133-43. Epub 10/26/2015.
Uddin MN, Lebel RM, Wilman AH
Magnetic resonance imaging.. 2016 January 34 (1):51-9. Epub 10/03/2015.
Uddin MN, Marc Lebel R, Wilman AH
Magnetic resonance in medicine.. 2013 November 70 (5):1340-6. Epub 01/16/2013.
Uddin, MN; Morrow MR.
Langmuir. 2010; 26(14): 12104-11.