Martha L. Blair, Ph.D.
Contact
Martha L. Blair, Ph.D.
About Me
Faculty Appointments
Professor Emeritus - Department of Pharmacology and Physiology (SMD)
Credentials
Post-doctoral Training & Residency
Neuroendocrinology (Postdoctoral Sponsor: Wm. F. Ganong), Department of Physiology, University of California at San Francisco 1974 - 1977
Education
PhD | University of Washington. Physiology & Psychology. 1974
BA | Wellesley College. Psychology. 1969
Awards
Dean's Teaching Fellow. 1988 - 1991
Commendation for excellence in first-year medical teaching, University of Rochester School of Medicine and Dentistry 1987
Mellon Foundation Fellow 1985 - 1988
Manuel Goldman Award for Excellence in Medical Teaching, University of Rochester School of Medicine and Dentistry 1983
Research Career Development Award. 1982 - 1987
Commendation for excellence in first-year medical teaching, University of Rochester School of Medicine and Dentistry 1982
Commendation for excellence in first-year medical teaching, University of Rochester School of Medicine and Dentistry 1981
Mellon Foundation Fellow 1979 - 1982
Young Investigator Award. 1978 - 1981
Sigma Xi. 1969
Research
Our primary research focus is on neural control of the renin-angiotensin system. Renin is a proteolytic enzyme which is secreted by the kidney and results in formation of the peptide hormone angiotensin. Renin secretion increases whenever blood pressure or blood volume decreases below normal levels. Angiotensin causes blood vessels to constrict, and has multiple additional actions which serve to elevate arterial blood pressure and defend blood volume. Our research employs physiological, pharmacological, and neuroanatomical techniques to evaluate the central nervous system and peripheral autonomic pathways that regulate renin release during cardiovascular challenges such as hemorrhage.
We have recently begun to investigate the effects of the female reproductive cycle in cardiovascular regulation. The majority of cardiovascular research has been performed in male subjects. However, recent evidence suggests that estrogen and progesterone may affect multiple facets of cardiovascular regulation. Our recent studies indicate that the ability to restore blood volume after a hemorrhage is significantly affected by the female reproductive cycle. This is an ongoing topic of research.
Publications
Journal Articles
Suppression of Prostate Cancer Cell Rolling and Adhesion to Endothelium by 1 alpha, 25-Dihydroxyvitamin D3
Hsu, JW; Yasmin-Karim, S; King,M.R.; Wojciechowski, JC; Mickelsen, D.; Blair, M.L.; Ting, HJ; Ma, WL; Lee YF;.
American Journal of Pathology. 2011; .
Wojciechowski JC, Narasipura SD, Charles N, Mickelsen D, Rana K, Blair ML, King MR
British journal of haematology.. 2008 March 140 (6):673-81. Epub 01/22/2008.
Sex-based differences in physiology: what should we teach in the medical curriculum?
Blair, M.L.
Adv. Physiol. Educ. 2007; 31: 23-25.
Blair ML, Mickelsen D
American journal of physiology. Regulatory, integrative and comparative physiology.. 2006 September 291 (3):R742-50. Epub 03/30/2006.
Blair ML, Mickelsen D
American journal of physiology. Regulatory, integrative and comparative physiology.. 2006 February 290 (2):R425-34. Epub 09/15/2005.
Radke KJ, King KB, Blair ML, Fitzpatrick PG, Eldredge DH
Heart & lung : the journal of critical care.. 2005 34 (2):126-35. Epub 1900 01 01.
Jaworski RL, Blair ML
Brain research bulletin.. 2004 July 1563 (6):451-9. Epub 1900 01 01.
Jaworski RL, Piekut D, Blair ML
Brain research bulletin.. 2002 March 1557 (5):595-602. Epub 1900 01 01.
Blair ML, Jaworski RL, Want A, Piekut DT
American journal of physiology. Regulatory, integrative and comparative physiology.. 2001 April 280 (4):R1141-8. Epub 1900 01 01.
Van de Kar LD, Blair ML
Frontiers in neuroendocrinology.. 1999 January 20 (1):1-48. Epub 1900 01 01.
Blair ML, Want A, Olschowka JA, Piekut D
The American journal of physiology.. 1998 July 275 (1):R278-85. Epub 1900 01 01.
Blair ML, Woolf PD, Felten SY
The American journal of physiology.. 1997 April 272 (4 Pt 2):R1197-203. Epub 1900 01 01.
Slimmer LM, Blair ML
The American journal of physiology.. 1996 September 271 (3 Pt 2):R626-33. Epub 1900 01 01.
Buske-Kirschbaum A, Grota L, Kirschbaum C, Bienen T, Moynihan J, Ader R, Blair ML, Hellhammer DH, Felten DL
Pharmacology, biochemistry, and behavior.. 1996 September 55 (1):27-32. Epub 1900 01 01.
Blair ML, Piekut D, Want A, Olschowka JA
Clinical and experimental pharmacology & physiology.. 1996 February 23 (2):161-5. Epub 1900 01 01.
Blair ML, Gengo FM
Canadian journal of physiology and pharmacology.. 1995 August 73 (8):1198-202. Epub 1900 01 01.
Blair ML, Hisa H, Sladek CD, Radke KJ, Gengo FM
The American journal of physiology.. 1991 June 260 (6 Pt 1):E910-9. Epub 1900 01 01.
Skoog KM, Blair ML, Sladek CD, Williams WM, Mangiapane ML
The American journal of physiology.. 1990 June 258 (6 Pt 2):R1472-8. Epub 1900 01 01.
Hisa H, Chen YH, Radke KJ, Izzo JL, Sladek CD, Blair ML
The American journal of physiology.. 1989 June 256 (6 Pt 1):E863-71. Epub 1900 01 01.
Mangiapane ML, Skoog KM, Rittenhouse P, Blair ML, Sladek CD
Circulation research.. 1989 January 64 (1):129-35. Epub 1900 01 01.
Chen YH, Hisa H, Radke KJ, Izzo JL, Sladek CD, Blair ML
The American journal of physiology.. 1988 December 255 (6 Pt 1):E793-800. Epub 1900 01 01.
Sladek CD, Blair ML, Sterling C, Mangiapane ML
Hypertension.. 1988 November 12 (5):506-12. Epub 1900 01 01.
Sladek CD, Devine MA, Felten SY, Aravich PF, Blair ML
Brain research.. 1988 March 29445 (1):39-46. Epub 1900 01 01.
Sladek CD, Chen YH, Aravich PF, Blair ML
Hypertension.. 1987 November 10 (5):476-83. Epub 1900 01 01.
Fink GD, Pawloski CM, Blair ML, Mangiapane ML
Hypertension.. 1987 June 9 (6 Pt 2):III206-9. Epub 1900 01 01.
Sladek CD, Blair ML, Mangiapane M
Hypertension.. 1987 April 9 (4):332-8. Epub 1900 01 01.
Davis BJ, Blair ML, Sladek JR, Sladek CD
Brain research.. 1987 March 3405 (1):1-15. Epub 1900 01 01.
Blair ML, Chen YH, Hisa H
The American journal of physiology.. 1986 December 251 (6 Pt 1):E695-702. Epub 1900 01 01.
Sladek CD, Blair ML, Chen YH, Rockhold RW
The American journal of physiology.. 1986 March 250 (3 Pt 2):H443-52. Epub 1900 01 01.
Blair ML, Chen YH, Izzo JL
The American journal of physiology.. 1985 March 248 (3 Pt 1):E317-26. Epub 1900 01 01.
Chen YH, Blair ML, Izzo JL
Journal of the autonomic nervous system. 1984 November 11 (3):285-95. Epub 1900 01 01.
Sladek CD, Blair ML
Hypertension.. 1984 6 (6 Pt 1):855-60. Epub 1900 01 01.
Blair ML
The American journal of physiology.. 1983 January 244 (1):E37-44. Epub 1900 01 01.
Sladek CD, Blair ML, Ramsay DJ
Endocrinology.. 1982 August 111 (2):599-607. Epub 1900 01 01.
Kass RS, Blair ML
Journal of molecular and cellular cardiology.. 1981 September 13 (9):797-809. Epub 1900 01 01.
Blair ML
The American journal of physiology.. 1981 June 240 (6):E682-8. Epub 1900 01 01.
Sladek CD, McNeill TH, Gregg CM, Blair ML, Baggs RB
Neurobiology of aging.. 1981 2 (4):293-302. Epub 1900 01 01.
Blair ML, Reid IA, Keil LC, Ganong WF
The Journal of pharmacology and experimental therapeutics.. 1979 September 210 (3):368-72. Epub 1900 01 01.
Blair ML, Reid IA, Ganong WF
The Journal of pharmacology and experimental therapeutics.. 1977 July 202 (1):209-15. Epub 1900 01 01.
Blair ML, Feigl EO, Smith OA
The American journal of physiology.. 1976 September 231 (3):772-6. Epub 1900 01 01.
Books
Drugs, Enzymes and Receptors of the Renin-Angiotensin System (2000)
Chapter: Renin secretion: Old concepts and new theories (Commentary)
Authors: Blair, M. L.
Publisher: Harwood Academic Publishers, Amsterdam 2000
Vasopressin (1991)
Chapter: Effects of vasopressin analogue in hypertension
Authors: Sladek, C.D., M.L. Blair, and M.L. Mangiapane
Publisher: John Libbey Eurotext Limited, London 1991