URMC / Pharmacology & Physiology / Events Seminars & Events The weekly colloquium is generally held on Thursdays at 2:00 p.m. in K-207 Auditorium (2-6408). Unless otherwise noted, our departmental colloquia program is supported by the Alejandro Zaffaroni Endowment Fund and the John R. Murlin Fund. For outside guests, contact Dr. Houhui Xia. For graduate student colloquia, contact Dr. Cesare Orlandi. Upcoming20242023202220212020Research Talk: “Isolating the Role of Myotonia in DM1 Pathogenesis”Matthew Sipple - Laboratory of Dr. John Lueck Dec 15, 2022 @ 12:30 p.m. Medical Center | Anders Room, 4-6912Or Join Zoom Research Talk: “Characterization of the Orai1-G100S Mouse Model of Tubular Aggregate Myopathy and Partial Rescue by Voluntary Wheel Running”Nan Zhao - Laboratory of Dr. Robert Dirksen Dec 08, 2022 @ 12:30 p.m. Medical Center | Anders Room, 4-6912Or Join Zoom Research Talk: "Calcium Channel Blockers as a Potential Therapeutic for DM1"Lily Cisco - Laboratory of Dr. John Lueck Dec 01, 2022 @ 12:30 p.m. Medical Center | Anders Room, 4-6912Or Join Zoom Ph.D. Thesis Defense: "KRIT1-mediated Regulation of Cellular Response to Inflammation"Nicholas Nobiletti - Advisor: Anglea J. Glading, Ph.D. Nov 30, 2022 @ 11:30 a.m. Medical Center | Case Method Room, 1-9576Or Join Zoom Guest Seminar: “Ablation of the MICOS complex Alters Mitochondrial Structural Changes in Skeletal and Cardiac Muscle During Aging”Antentor Othrell Hinton, Jr., Ph.D. - Assistant Professor Department of Molecular Physiology and Biophysics, Ernest E. Just Early Career Investigator, Member of the Vanderbilt Diabetes Research and Training Center at Vanderbilt University Nov 18, 2022 @ 2:00 p.m. Medical Center | Ryan Case Method Room (1-9576)Second-Year 20 minute Literature Reviews: “Selective Activation of Inhibitory-Class Gα Subtypes Confers Unique Pharmacological Effects at Adenosine A1 Receptors"Grant Grieble - Graduate Student in the Laboratory of Dr. Jean Bidlack Nov 10, 2022 @ 1:00 p.m. Medical Center | Anders Room, 4-6912Or Join Zoom Second-Year 20 minute Literature Reviews: “Astrocytes Propel Neurovascular Dysfunction During Cerebral Cavernous Malformation Lesion Formation"Rhodalyn Essien - Graduate Student in the Laboratory of Dr. Angela Glading Nov 10, 2022 @ 12:30 p.m. Medical Center | Anders Room, 4-6912Or Join Zoom "Synaptic Dysfunction Underlying Neurodevelopmental Disorders”Guest Speaker: Katherine W. Roche, Ph.D. - Senior Investigator, Receptor Biology Section NINDS, National Institutes of Health, Bethesda, MD Nov 03, 2022 @ 12:30 p.m. Medical Center | Ryan Case Method Room (1-9576)Or Join Zoom Ph.D. Thesis Defense: "Interrogation into Molecular Mechanisms of Activation and Desensitization in Acid-Sending Ion Channel 1a"Matthew L. Rook, Ph.D. - Advisor: David M. MacLean, Ph.D. Nov 01, 2022 @ 12:15 p.m. Medical Center | Case Method Room, 1-9576Or Join Zoom Second-Year 20 minute Literature Reviews: “Light-Activated Mitochondrial Fission Through Optogenetic Control of Mitochondrial-Lysosome Contacts”Nada Ahmed Selim - Graduate Student in the Laboratory of Dr. Andrew Wojtovich Oct 27, 2022 @ 1:00 p.m. Medical Center | Anders Room, 4-6912Or Join Zoom Second-Year 20 minute Literature Reviews: “Detection of Ca2+ Transients Near Ryanodine Receptors by Targeting Fluorescent Ca2+ Sensors to the Triad”Xiaoxuan Lin - Graduate Student in the Laboratory of Dr. David Yule Oct 27, 2022 @ 12:30 p.m. Medical Center | Anders Room, 4-6912Or Join Zoom 2022 Wallace O. Fenn Lecture: “Age-dependent Impairment of Neurovascular Coupling in a Col4a1 Mutant”Scott Earley, Ph.D. - Professor of Pharmacology Director, Center for Molecular and Cellular Signaling in the Cardiovascular System University of Nevada, Reno School of Medicine, Reno, NV Oct 13, 2022 @ 3:30 p.m. Medical Center | Ryan Case Method Room (1-9576)"Live-Animal Multiphoton Imaging of the Blood Stem Cell Niche"Guest Speaker: Shu-Chi (Allison) Yeh, Ph.D. - Assistant Professor, Department of Orthopedics, Center for Musculoskeletal Research, 鶹Ƶ Oct 06, 2022 @ 12:30 p.m. Medical Center | Anders Room, 4-6912Or Join Zoom (password: Seminar) Ph.D. Thesis Proposal: “Myelin Maturation in Macaque and Murine Striatum During Postnatal Development”Halima Aweis - (Advisor: Dr. Suzanne N. Haber) Sep 28, 2022 @ 2:00 p.m. Medical Center | Anders Room, 4-6912Or Join Zoom Ph.D. Thesis Proposal: “RpL17 Dependent Signaling in Endothelial Cells Inhibits Angiogenesis”Michal Shaposhnikov - (Advisor: Dr. Bradford C. Berk) Sep 22, 2022 @ 12:30 p.m. Medical Center | Case Method Room, 1-9576Or Join Zoom Ph.D. Thesis Proposal: “Epigenetic Modifiers of Malignant Hyperthermia”Miao He - (Advisor: Dr. Robert Dirksen) Sep 19, 2022 @ 11:00 a.m. Medical Center | Anders Room, 4-6912Or Join Zoom "Vascular and Immune Mechanisms of Hypertension: Role of Cullin3 Ubiquitin Ligase"Guest Speaker: Jing (Jason) Wu, Ph.D. - Assistant Professor of Medicine, Division of Nephrology, 鶹Ƶ Sep 01, 2022 @ 12:30 p.m. Medical Center | Anders Room, 4-6912Or Join Zoom (password: Seminar) Ph.D. Thesis Proposal: "The Role of Small Proline-Rich Protein 2b (SPRR2B) in Regulating Cardiac Fibrosis"Xiaoyi Liu - (Advisor: Dr. Eric Small) Aug 29, 2022 @ 1:00 p.m. Medical Center | K-307, 3-6408Or Join Zoom Ph.D. Thesis Proposal: “Role of Orphan G Protein-coupled Receptor GPRC5B in Retinoic Acid-induced Depressive-like Behaviors”Wenqi Fu - (Advisor: Dr. Cesare Orlandi) Aug 25, 2022 @ 12:30 p.m. Medical Center | Case Method Room, 1-9576Or Join Zoom Ph.D. Thesis Defense: “Topography and Motion of the Acid-sensing Ion Channel 1 Intracellular Domains”Tyler A. Couch - (Advisor: David M. MacLean, Ph.D.) Jul 14, 2022 @ 12:30 p.m. Medical Center | Case Method Room, 1-9576Or Join Zoom Ph.D. Thesis Defense: "Investigating Succinate and pH Dynamics in Cardiac Ischemia-Reperfusion Injury"Alexander S. Milliken - (Advisor: Paul S. Brookes, Ph.D.) Jun 16, 2022 @ 12:00 p.m. Medical Center | Case Method Room, 1-9576Or Join Zoom First-Year Rotation Talks: “Chimeric Antigen Receptors (CAR’s)”Fatemeh Alimohammadi - Graduate Student in the Laboratory of Dr. Minsoo Kim May 19, 2022 @ 1:00 p.m. Medical Center | Anders Room, 4-6912Or Join Zoom First-Year Rotation Talks: “Piezo1 Channels as Targets in the Treatment of Osteoarthritis”Alireza Mousaei - Graduate Student in the Laboratory of Dr. Whasil Lee May 19, 2022 @ 12:30 p.m. Medical Center | Anders Room, 4-6912Or Join Zoom "The cytoskeleton as disease modifier in striated muscle"Chris W. Ward, Ph.D. - Professor, Department of Orthopedics, University of Maryland School of Medicine May 18, 2022 @ 12:00 p.m. Medical Center | Anders Room, 4-6912Or Join Zoom (Passcode: Seminar) First-Year Rotation Talks: "The effect of modified Cyclophilin D (CypD) on mitochondrial function in HEK293 cells"Xiaoxuan Lin - Graduate Student in the Laboratory of Dr. George Porter May 12, 2022 @ 1:00 p.m. Medical Center | Anders Room, 4-6912Or Join Zoom First-Year Rotation Talks: "Using Molecular Dynamics Strategies to Elucidate Therapeutic Effects of D-cysteine ethyl ester (DCee) in Treating Opioid Overdose"Grant Grieble - Graduate Student in the Laboratory of Dr. Alan Grossfield May 12, 2022 @ 12:30 p.m. Medical Center | Anders Room, 4-6912Or Join Zoom Research Talk: "Functional Analyses of Acidic Pocket Collapse in ASIC1a via Pharmacology and Photo Crosslinking"Matthew Rook - Laboratory of Dr. David MacLean Apr 28, 2022 @ 12:30 p.m. Medical Center | Anders Room, 4-6912Or Join Zoom Research Talk: "Salivary Ducts – Linking Structure to Function"Amanda Wahl - Laboratory of Dr. David Yule Apr 21, 2022 @ 12:30 p.m. Medical Center | Anders Room, 4-6912Or Join Zoom Inner retinal hyperactivity in degenerative blindness: Molecular mechanisms, Cellular sources, and physiological consequencesMichel Telias, PhD - Assistant Professor, Department of Ophthalmology and Neuroscience Apr 14, 2022 @ 12:30 p.m. Medical Center | K-207 (2-6408)Host: Pharmacology and Physiology and Cellular and Molecular Pharmacology and Physiology ProgramResearch Talk: “KRIT1-Mediated Regulation of Neutrophil Adhesion and Motility”Nick Nobiletti - Laboratory of Dr. Angela Glading Apr 07, 2022 @ 12:30 p.m. Medical Center | Anders Room, 4-6912Or Join Zoom “Alteration of Ca2+ signaling and compromised mitochondria in the early stages of Sjogren’s syndrome mouse model.”Kai-Ting Huang - Graduate Student in the laboratory of Dr. David I. Yule Mar 24, 2022 @ 12:30 p.m. Medical Center | Anders Room, 4-6912Or Join Zoom Ph.D. Thesis Defense: "A Comprehensive Overview of Metabotropic Glutamate Receptor Dimer Signaling"Tyler McCullock - (Advisor: Paul Kammermeier, Ph.D.) Mar 17, 2022 @ 12:30 p.m. Medical Center | Adolph Auditorium, 1-7619Or Join Zoom Second-Year 25 minute Literature Reviews: "Characterization of 5HT1A receptor coupling profile"Rana Alabdali - Graduate Student in the Laboratory of Dr. Cesare Orlandi Mar 10, 2022 @ 1:00 p.m. Medical Center | Anders Room, 4-6912Or Join Zoom Second-Year 25 minute Literature Reviews: “The role of small proline-rich protein 2b in the cardiac fibrosis”Xiaoyi Liu - Graduate Student in the Laboratory of Dr. Eric Small Mar 10, 2022 @ 12:30 p.m. Medical Center | Anders Room, 4-6912 Or Join Zoom "Development of a Novel Agent with Dual Anti-resporptive and Anabolic Effect for the treatment of Osteoporosis"Zhenqiang Yao, B. Med., Ph.D. - Assistant Professor, Department of Pathology and Laboratory Medicine, 鶹Ƶ Mar 03, 2022 @ 12:30 p.m. Medical Center | K-207, 2-6408Or Join Zoom (Passcode: Seminar) M4 muscarinic receptor modulation of striatal biology and repetitive behaviorsDaniel J. Foster, Ph.D. - Faculty Candidate, Research Assistant Professor, Department of Pharmacology; Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN Feb 28, 2022 @ 9:00 a.m. Medical Center | K307, Room 3-6408Or Join Zoom (Passcode:Seminar) Second-Year 25 minute Research Talks: "RpL17 and signaling in angiogenesis"Michal Shaposhnikov - Graduate Student in the Laboratory of Dr. Bradford Berk Feb 24, 2022 @ 1:00 p.m. Medical Center | Anders Room, 4-6912Or Join Zoom Second-Year 25 minute Research Talks: "SOCE dysfunction in a new calsequestrin mouse model of tubular aggregate myopathy"Maio He - Graduate Student in the Laboratory of Dr. Robert Dirksen Feb 24, 2022 @ 12:30 p.m. Medical Center | Anders Room, 4-6912Or Join Zoom Second-Year 25 minute Literature Reviews: “Comprehensive spatial profiling of the orphan G protein coupled receptor GPRC5B in mouse brain”Wenqi Fu - Graduate Student in the Laboratory of Dr. Cesare Orlandi Feb 17, 2022 @ 1:00 p.m. Medical Center | Anders Room, 4-6912Or Join Zoom Link Second-Year 25 minute Literature Reviews: "Myelin Development in Striatum"Halima Aweis - Graduate Student in the Laboratory of Dr. Suzanne Haber Feb 17, 2022 @ 12:30 p.m. Medical Center | Anders Room, 4-6912Or Join Zoom Link Fixing broken connections: GABA and glutamate neurotransmitter deficits in depression and reversal by novel treatmentsManoela V. Fogaca, Ph.D. - Faculty Candidate, Postdoctoral Fellow, Department of Psychiatry, CHMC, Yale School of Medicine, New Haven, CT Feb 10, 2022 @ 9:00 a.m. Medical Center | Adolph Auditorium Room 1-7619Or Join Zoom (Passcode: Seminar) Ph.D. Thesis Defense: "Electroporation Mediated Gene Delivery to Rescue the Alveolar Capillary Barrier Function for ARDS Treatment"Jing Liu - Graduate Student in the laboratory of Dr. David Dean Feb 02, 2022 @ 9:30 a.m. Medical Center | K-307, 3-6408Or Join Zoom Research Talk: "Efficient Suppression of Endogenous CFTR Nonsense Mutations Using Anticodon Engineered Transfer RNAs"Wooree Ko - Laboratory of Dr. John Lueck Jan 27, 2022 @ 12:30 p.m.Join Zoom Investigating the Physiology of Adhesion-Class GPCRs in the KidneyNathan Zaidman, Ph.D. - Faculty Candidate, Postdoctoral Fellow Department of Physiology John Hopkins University School of Medicine Baltimore, Maryland Jan 25, 2022 @ 8:30 a.m. Medical Center | Adolph (lower) Auditorium, 1-7619Or Join Zoom (Passcode: Seminar) Creating a metabolomics pipeline for investigating gut microbiome-host interactionsShuo Han, Ph.D. - Faculty Candidate, Postdoctoral Fellow, Department of Microbiology and Immunology Stanford University School of Medicine Stanford, CA Jan 19, 2022 @ 10:00 a.m.Join Zoom (Passcode: Seminar) Unique development plasticity and function of frontal cortical dopamine circuitsKuan Hong Wang Jan 13, 2022 @ 12:30 p.m. Medical Center | Or Join Zoom